Restriction Fragment Length Polymorphism Linkage Map for Arabidopsis thaliana [PDF]
, 1988 We have constructed a restriction fragment length polymorphism linkage map for the nuclear genome of the flowering plant Arabidopsis thaliana. The map, containing 90 randomly distributed molecular markers, is physically very dense; >50% of the genome is ...
Bowman, John L. +4 more
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A Germline Variant at 8q24 Contributes to the Serum p2PSA Level in a Chinese Prostate Biopsy Cohort
Frontiers in Oncology, 2021 IntroductionThe clinical performance of [–2]proPSA (p2PSA) and its derivatives in predicting the presence and aggressiveness of prostate cancer (PCa) has been well evaluated in prostate biopsy patients.
Xiaoling Lin +22 more
doaj +1 more source
Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity [PDF]
, 2004 Introduction Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter
Azmy, I.A.F. +6 more
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Circulating MicroRNA Expression Levels Associated With Internet Gaming Disorder
Frontiers in Psychiatry, 2018 BackgroundAddictive use of the Internet and online games is a potential psychiatric disorder termed Internet gaming disorder (IGD). Altered microRNA (miRNA) expression profiles have been reported in blood and brain tissue of patients with certain ...
Minho Lee +19 more
doaj +1 more source
Human leukocyte antigen class I, class II, and tumor necrosis factor-alpha polymorphisms in a healthy elder Mexican Mestizo population [PDF]
, 2005 BACKGROUND: There is strong evidence that an individual's genetic background is an important predisposing factor to longevity. In the present study we analysed the frequency of HLA class I, class II, as well as the TNF-α -308 polymorphism that may be ...
Llorente, Luis +2 more
core +3 more sources
Perspectives and Challenges in the Fight Against COVID-19: The Role of Genetic Variability
Frontiers in Cellular and Infection Microbiology, 2021 In the last year, the advent of the COVID-19 pandemic brought a new consideration for the multidisciplinary sciences. The unknown mechanisms of infection used by SARS-CoV-2 and the absence of effective antiviral pharmacological therapy, diagnosis methods,
Mariana Guilger-Casagrande +5 more
doaj +1 more source
A critique of avian CHD-based molecular sexing protocols illustrated by a Z-chromosome polymorphism detected in auklets [PDF]
, 2001 The sexes of non-ratite birds can be determined routinely by PCR amplification of the CHD-Z and CHD-W genes. CHD -based molecular sexing of four species of auklets revealed the presence of a polymorphism in the Z chromosome.
Burke, T. +5 more
core +1 more source
Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide [PDF]
, 2010 The association between suicide and G-703T polymorphism of the tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was studied in a sample of 291 suicide victims and 280 healthy subjects of ...
Bakula, Mirko +6 more
core +1 more source
Experimental and Molecular Medicine, 2018 Prostate cancer: Promising protein biomarker A protein found in high levels in prostate cancer tissues could provide a biomarker and therapeutic target for the disease.
Jieying Liu +7 more
doaj +1 more source
Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]
, 2002 Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
de Jaegere, Peter +10 more
core +1 more source