Results 31 to 40 of about 727,358 (304)

Pathogenic NF1 truncating mutation and copy number alterations in a dedifferentiated liposarcoma with multiple lung metastasis: a case report

open access: yesBMC Medical Genetics, 2020
Background Dedifferentiated liposarcoma (DDLPS), which accounts for an estimated 15–20% of liposarcomas, is a high-grade and aggressive malignant neoplasm, exhibiting a poor response to available therapeutic agents.
Yoon-Seob Kim   +3 more
doaj   +1 more source

Interactions Between Glycogen Synthase Kinase-3β Gene Polymorphisms, Negative Life Events, and Susceptibility to Major Depressive Disorder in a Chinese Population

open access: yesFrontiers in Psychiatry, 2021
Background: Recent studies suggest that glycogen synthase kinase (GSK)-3β is involved in the development of major depressive disorder (MDD). The aim of this study was to investigate the interaction between GSK-3β polymorphism (rs6438552, rs334558, and ...
Jiarun Yang   +11 more
doaj   +1 more source

Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide [PDF]

open access: yes, 2010
The association between suicide and G-703T polymorphism of the tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was studied in a sample of 291 suicide victims and 280 healthy subjects of ...
Bakula, Mirko   +6 more
core   +1 more source

A critique of avian CHD-based molecular sexing protocols illustrated by a Z-chromosome polymorphism detected in auklets [PDF]

open access: yes, 2001
The sexes of non-ratite birds can be determined routinely by PCR amplification of the CHD-Z and CHD-W genes. CHD -based molecular sexing of four species of auklets revealed the presence of a polymorphism in the Z chromosome.
Burke, T.   +5 more
core   +1 more source

Survey of Blood Groups DEA 1, DEA 4, DEA 5, Dal, and Kai 1/Kai 2 in Different Canine Breeds From a Diagnostic Laboratory in Germany

open access: yesFrontiers in Veterinary Science, 2020
More than twelve blood group systems have been described in dogs, but little is known about their distribution frequencies within breed populations. Here, we report on an extensive typing survey carried out using available reagents and either established
Anne K. Ebelt   +4 more
doaj   +1 more source

Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]

open access: yes, 2002
Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
de Jaegere, Peter   +10 more
core   +1 more source

Polygenes and polymorphism

open access: yesMolecular and General Genetics MGG, 1967
Uploaded by Plazi for TaxoDros. We do not have abstracts.
S. M. W. Hosgood   +2 more
openaire   +4 more sources

Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity [PDF]

open access: yes, 2004
Introduction Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter
Azmy, I.A.F.   +6 more
core   +2 more sources

Circulating MicroRNA Expression Levels Associated With Internet Gaming Disorder

open access: yesFrontiers in Psychiatry, 2018
BackgroundAddictive use of the Internet and online games is a potential psychiatric disorder termed Internet gaming disorder (IGD). Altered microRNA (miRNA) expression profiles have been reported in blood and brain tissue of patients with certain ...
Minho Lee   +19 more
doaj   +1 more source

Dissecting the Association of Apolipoprotein E Gene Polymorphisms With Type 2 Diabetes Mellitus and Coronary Artery Disease

open access: yesFrontiers in Endocrinology, 2022
BackgroundApolipoprotein E (APOE) gene mediates lipoprotein clearance and is one of the most studied candidate genes for type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD). This study was performed to determine the association between APOE
Lei Wu   +13 more
doaj   +1 more source

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