Results 121 to 130 of about 62,432 (254)

Factors affecting the pathogenicity of Yersinia ruckeri [PDF]

open access: yes, 1990
A group of 42 strains of Yersinia ruckeri were characterized and found to show homogenous biochemical profiles. The optimal conditions for in vitro culture of a representative strain of Y. ruckeri were established.
Nozal, Maria Dolores Furones
core   +1 more source

Successful Management of Suspected Epstein–Barr Virus‐Associated Hemophagocytic Lymphohistiocytosis in BRAF‐Mutant Cholangiocarcinoma Following Treatment With Immune Checkpoint Inhibitors and BRAF/MEK Inhibitors: A Case Report

open access: yesCancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background The BRAF V600E mutation is a rare genetic alteration in cholangiocarcinoma for which sequential therapy with immune checkpoint inhibitors (ICIs) and BRAF/MEK inhibitors may be effective. However, the full spectrum of adverse events associated with the sequential use of these agents remains unclear. Hemophagocytic lymphohistiocytosis
Akira Shibata   +9 more
wiley   +1 more source

Molecular modeling study of the contributions of side amino acid residues of polymyxin B3 to its binding with E.coli outer membrane lipopolysaccharide

open access: yesAnnals of Mechnikov's Institute, 2020
Last decades, antimicrobial peptides (AMPs) are the subject of intense investigations aimed to develop effective drugs against extremely resistant nosocomial bacterial pathogens (especially Gram-negative bacteria).
Yu Lisnyak
doaj  

Feasibility of Recycled Polypropylene for Reusable Food Packaging: Effects of Reuse Conditions on Packaging Performance, Material Properties, and Microbial Safety

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
This study demonstrates that postindustrial recycled polypropylene (PIR PP) performs comparably to virgin polypropylene in reusable food packaging. After 20 simulated reuse cycles, including heating and commercial washing, PIR PP retained its structural, chemical, and microbial safety properties, supporting its potential for safe and sustainable ...
Caolan Jameson   +7 more
wiley   +1 more source

Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary cells in the presence of adenovirus [PDF]

open access: yes, 1994
Endotoxin (lipopolysaccharide, LPS) is commonly found as a contaminant in plasmid DNA preparations. We demonstrate here that the quantities of LPS typically contaminating DNA preparations can generate a toxicity to primary cells (primary human skin ...
Baker, A.   +4 more
core  

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

Polymyxin Including Therapy Versus Colistin Including Therapy In The Therapy Of Carbapenem-Resistant Gram-Negative Infections: A Retrospective Matched Cohort Study

open access: yesJournal of Global Antimicrobial Resistance
BACKGROUND-AIM: In this retrospective matched cohort study, we aimed to compare the clinical outcomes of polymyxin b (PMXB) including therapy receiving cases with colistin receiving cases on culture-proven carbapenem-resistant Gram-negative infections ...
Merve Mert Vahabi   +19 more
doaj   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Biofilm and surface-motility profiles under polymyxin B stress in multidrug-resistant KAPE pathogens isolated from Ghanaian hospital ICUs

open access: yesExperimental Biology and Medicine
The threat of antimicrobial resistance in Ghana is increasing with the recent emergence of KAPE pathogens (K. pneumoniae, A. baumannii, P. aeruginosa and Enterobacter species) from the hospital environment.
Molly K. Abban   +5 more
doaj   +1 more source

Graphene Triggers Inflammation in Murine Microglia via Phagocytosis

open access: yesSmall Science, Volume 6, Issue 3, March 2026.
Phagocytosis of single‐layer graphene by microglia triggers inflammatory activation without cytotoxicity. Small carbon nanotubes elicit similar responses, whereas larger graphene nanoplatelets do not. Proteomic analysis reveals effects on inflammation, cytoskeleton, and proliferation, highlighting the importance of graphene stability for safe neural ...
Pratika Rai   +10 more
wiley   +1 more source

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