Results 91 to 100 of about 41,111 (239)
An Update on the arsenal for multidrug-resistant Acinetobacter infections: Polymyxin antibiotics
International Journal of Infectious Diseases, 2015 Objective: To review recent clinical pharmacokinetic and pharmacodynamic data to optimize dosing regimens for polymyxin B and colistin for treatment of infections due to A. baumannii.
Zahra Kassamali +2 more
doaj +1 more source
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT This study compared tear film exposure and retention of four chloramphenicol ophthalmic formulations in dogs, evaluating the effects of drug concentration (0.2% to 5%) and vehicle type (solution vs. ointment). Eight healthy dogs were enrolled in a randomized paired‐eye crossover study consisting of two sessions with a 7‐day washout.
Bar Fruchter +3 more
wiley +1 more source
Polymyxin B broth disk elution as a screening test to determine polymyxin B susceptibility in enterobacterales [PDF]
, 2019 Detection of polymyxins susceptibility by clinical laboratories is a nightmare mainly because of physicochemical properties of the drug. The aim of this study was to evaluate accuracy of Polymyxin B Broth Disk Elution (PBDE), as screening test, compared ...
Cielo, Naiany Canabarro
core
Polymyxin B use does not ensure endotoxin-free solution [PDF]
, 1985 Polymyxin B is often added to in vitro samples to `ensure' that endotoxin activity is removed. We present data, from the standard rabbit pyrogen test and the Limulus amebocyte lysate assay, that polymyxin B bound to a gel support will bind some, but not ...
Eiger, Steven M. +2 more
core +1 more source
Computational and Structural Biotechnology Journal, 2018 Polymyxins are amongst the most important antibiotics in modern medicine, in recent times their clinical utility has been overshadowed by nosocomial outbreaks of polymyxin resistant MDR Gram-negative ‘superbugs’.
Maytham Hussein +11 more
doaj +1 more source
Molecular Microbiology, EarlyView.Host tissue cues including temperature, oxygen, and iron availability regulate expression of the Yersinia type III secretion system (T3SS) master regulator LcrF. We found that CpxR inhibits LcrF through an indirect, multi‐factorial mechanism and identified the osmolarity‐sensing OmpR/EnvZ system as an additional regulator of LcrF, highlighting ...
Karen Hug +8 more
wiley +1 more source
Optimization of polymyxin B in combination with doripenem to combat mutator Pseudomonas aeruginosa [PDF]
, 2016 Development of spontaneous mutations in Pseudomonas aeruginosa has been associated with antibiotic failure, leading to high rates of morbidity and mortality.
Holden, Patricia N +8 more
core +1 more source
Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States
Veterinary Dermatology, EarlyView.ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro +2 more
wiley +1 more source
A Comparative Study on Efficacy of Polymyxin B, Neomycin and Polymyxin B, Neomycin, Hydrocortisone in the Treatment of Otitis Externa at Nepal Medical College and Teaching Hospital, Kathmandu [PDF]
, 2017 IntroductionAcute otitis externa (AOE) is a common but preventable ear condition. Tenderness with movement of the tragus or pinna is a classic feature of otitis Externa.
Mayuri Gupta, S Aryal
core +1 more source
Journal of Infection and Public HealthBackground: Studies comparing colistin and polymyxin B minimum inhibitory concentrations (MICs), as well as their correlation and agreement, using non-commercial broth microdilution methods, remain limited.
Yu-Shan Huang +4 more
doaj +1 more source