Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria [PDF]
Polymyxins are polycationic antimicrobial peptides that are currently the last-resort antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections.
Morand, Serge +2 more
core +3 more sources
Background: Studies comparing colistin and polymyxin B minimum inhibitory concentrations (MICs), as well as their correlation and agreement, using non-commercial broth microdilution methods, remain limited.
Yu-Shan Huang +4 more
doaj +1 more source
Neurotrophic keratitis after micropulse transscleral diode laser cyclophotocoagulation. [PDF]
PurposeTo report two cases of neurotrophic keratitis (NK) after micropulse transscleral cyclophotocoagulation (MP-TCP).ObservationsTwo patients with predisposing factors for decreased corneal sensation developed NK 1 month after MP-TCP. Both patients did
Han, Ying +4 more
core +1 more source
\u3cem\u3eRhizobium etli\u3c/em\u3e CE3 Bacteroid Lipopolysaccharides Are Structurally Similar but Not Identical to Those Produced by Cultured CE3 Bacteria [PDF]
Rhizobium etli CE3 bacteroids were isolated from Phaseolus vulgaris root nodules. The lipopolysaccharide (LPS) from the bacteroids was purified and compared with the LPS from laboratory-cultured R.
Carlson, Russell W. +4 more
core +1 more source
Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]
Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio +8 more
core +2 more sources
Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum [PDF]
In vitro models that mimic in vivo host-pathogen interactions are needed to evaluate candidate drugs that inhibit bacterial virulence traits. We established a new approach to study Pseudomonas aeruginosa biofilm susceptibility on biotic surfaces, using a
Coenye, Tom +11 more
core +1 more source
Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here,
Suneel Kumar Garg +7 more
doaj +1 more source
Propionibacterium acnes infections in patients with idiopathic scoliosis: a case-control study and review of the literature. [PDF]
Purpose:Surgical site infection (SSI) caused by Propionibacterium acnes is an infrequent but devastating complication after spinal fusion. The purpose of this study was to identify risk factors for SSI with Propionibacterium acnes after spinal fusion for
Blanco, J +6 more
core +2 more sources
Nitazoxanide synergizes polymyxin B against Escherichia coli by depleting cellular energy
The rapid expansion of antibiotic-resistant bacterial diseases is a global burden on public health. It makes sense to repurpose and reposition already-approved medications for use as supplementary agents in synergistic combinations with existing ...
Xuejia Jiang +8 more
doaj +1 more source
Role of BacA in Lipopolysaccharide Synthesis, Peptide Transport, and Nodulation by \u3cem\u3eRhizobium\u3c/em\u3e sp. Strain NGR234 [PDF]
BacA of Sinorhizobium meliloti plays an essential role in the establishment of nitrogen-fixing symbioses with Medicago plants, where it is involved in peptide import and in the addition of very-long-chain fatty acids (VLCFA) to lipid A of ...
Ardissone, Silvia +7 more
core +1 more source

