Results 61 to 70 of about 12,305,089 (195)

Effectiveness and safety of polymyxin B for the treatment of infections caused by extensively drug-resistant Gram-negative bacteria in Thailand

, 2018
Thundon Ngamprasertchai,1 Adhiratha Boonyasiri,2 Lantharita Charoenpong,3 Sireethorn Nimitvilai,4 Narisorn Lorchirachoonkul,5 Luksame Wattanamongkonsil,2 Visanu Thamlikitkul6 1Department of Clinical Tropical Medicine, Faculty of Tropical Medicine ...
Lorchirachoonkul N, Charoenpong L, Ngamprasertchai T, Boonyasiri A, Wattanamongkonsil L, Thamlikitkul V, Nimitvilai S   +6 more
core  

The action of polymyxin B at the frog neuromuscular juntion

, 1981
The effects of polymyxin B at the neuromuscular junction of the frog were studied by conventional electrophysiological and voltage clamp techniques. At a concentration of 2.5 μg/ml polymyxin B produced neuromuscular blockade in 10 to 15 min and endplate ...
NICHOLAS N. DURANT, Durant, Nicholas N., Lambert, Jeremy J., JEREMY J. LAMBERT   +3 more
core   +1 more source

Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aeruginosa

Computational and Structural Biotechnology Journal, 2018
Polymyxins are amongst the most important antibiotics in modern medicine, in recent times their clinical utility has been overshadowed by nosocomial outbreaks of polymyxin resistant MDR Gram-negative ‘superbugs’.
Maytham Hussein, Mei-Ling Han, Yan Zhu, Elena K. Schneider-Futschik, Xiaohan Hu, Qi Tony Zhou, Yu-Wei Lin, Dovile Anderson, Darren J. Creek, Daniel Hoyer, Jian Li, Tony Velkov   +11 more
doaj   +1 more source

Table_3_Ceftazidime/avibactam Improves the Antibacterial Efficacy of Polymyxin B Against Polymyxin B Heteroresistant KPC-2-Producing Klebsiella pneumoniae and Hinders Emergence of Resistant Subpopulation in vitro.docx

, 2019
Due to the increasing multidrug resistance and limited antibiotics, polymyxin B revived as the last resort for the treatment of carbapenemase-producing Klebsiella pneumoniae (CRKP).
Jianming Zeng (2138470), Bin Huang (331329), Xuegao Yu (7180088), Yang Lu (59885), Liang Chen (73736), Yimei Cai (52714), Renxin Cai (7339241), Yuting He (3821419), Xingyan Ma (7180097), Cha Chen (385771)   +9 more
core   +1 more source

Comparative analysis of colistin and polymyxin B minimal inhibitory concentrations in Enterobacterales, Acinetobacter baumannii, and Pseudomonas aeruginosa

Journal of Infection and Public Health
Background: Studies comparing colistin and polymyxin B minimum inhibitory concentrations (MICs), as well as their correlation and agreement, using non-commercial broth microdilution methods, remain limited.
Yu-Shan Huang, Jann-Tay Wang, Yu-Chung Chuang, Wang-Huei Sheng, Shan-Chwen Chang   +4 more
doaj   +1 more source

THE RELEASE OF HISTAMINE BY POLYMYXIN B AND POLYMYXIN E [PDF]

British Journal of Pharmacology and Chemotherapy, 1955
S R, BUSHBY, A F, GREEN
openaire   +2 more sources

Structure-function studies of polymyxin B lipononapeptides

, 2019
The emerging threat of infections caused by highly drug-resistant bacteria has prompted a resurgence in the use of the lipodecapeptide antibiotics polymyxin B and colistin as last resort therapies.
Blaskovich, Mark, Hansford, Karl, Mark S. Butler, Matthew A. Cooper, Cooper, Matthew, Matthew A. Cooper, Mark A. T. Blaskovich, Johnny X. Huang, Johnny X. Huang, Mark S. Butler, Karl A. Hansford, Craig Muldoon, Elliott, Alysha, Alejandra Gallardo-Godoy, Ruby Pelingon, Karl A. Hansford, Butler, Mark, Mark A. T. Blaskovich, Bernd Becker, Huang, Johnny, Gallardo-Godoy, Alejandra, Muldoon, Craig, Alysha G. Elliott, Alysha G. Elliott, Pelingon, Ruby, Becker, Bernd   +25 more
core   +1 more source

Molecular analysis of polymyxin B resistance in clinical carbapenem-resistant Klebsiella pneumoniae isolates from a large tertiary care teaching hospital in Southwest China

BMC Microbiology
Background This study aimed to investigate the molecular basis of polymyxin B resistance in clinical carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates.
Siying Wu, Quanfeng Liao, Ya Liu, Jin Deng, Weili Zhang, Mei Kang   +5 more
doaj   +1 more source

Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence

Critical Care Research and Practice, 2017
Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here,
Suneel Kumar Garg, Omender Singh, Deven Juneja, Niraj Tyagi, Amandeep Singh Khurana, Amit Qamra, Salman Motlekar, Hanmant Barkate   +7 more
doaj   +1 more source

Table_1_Ceftazidime/avibactam Improves the Antibacterial Efficacy of Polymyxin B Against Polymyxin B Heteroresistant KPC-2-Producing Klebsiella pneumoniae and Hinders Emergence of Resistant Subpopulation in vitro.docx

, 2019
Due to the increasing multidrug resistance and limited antibiotics, polymyxin B revived as the last resort for the treatment of carbapenemase-producing Klebsiella pneumoniae (CRKP).
Jianming Zeng (2138470), Bin Huang (331329), Xuegao Yu (7180088), Yang Lu (59885), Liang Chen (73736), Yimei Cai (52714), Renxin Cai (7339241), Yuting He (3821419), Xingyan Ma (7180097), Cha Chen (385771)   +9 more
core   +1 more source