Results 101 to 110 of about 15,147 (259)
Allergy, EarlyView.Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud +23 more
wiley +1 more source
Pseudomonas aeruginosa MipA-MipB envelope proteins act as new sensors of polymyxins
mBioDue to the rising incidence of antibiotic-resistant infections, the last-line antibiotics, polymyxins, have resurged in the clinics in parallel with new bacterial strategies of escape.
Manon Janet-Maitre +9 more
doaj +1 more source
MCR: modern colistin resistance [PDF]
, 2017 Recently, plasmid-mediated and, therefore, transferable bacterial polymyxin resistance was discovered in strains from both humans and animals. Such a trait may widely spread geographically, while simultaneously crossing microbial species barriers. This
Belkum, A. van +4 more
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Evaluation of three broth microdilution systems to determine colistin susceptibility of Gram-negative bacilli [PDF]
, 2018 The broth microdilution (BMD) method is currently the recommended technique to determine susceptibility to colistin.Objectives: We evaluated the accuracy of three commercialized BMD panels [Sensititre (ThermoFisher Diagnostics), UMIC (Biocentric) and ...
André, Catherine +4 more
core +2 more sources
Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis
BJU International, EarlyView.Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon +3 more
wiley +1 more source
A series of clinical cases highlighting cardiotoxicity induced by polymyxin B
Emergency Care JournalPolymyxins, particularly polymyxin B, have resurfaced as critical agents against Multidrug-Resistant Organisms (MDROs) despite their historical withdrawal from clinical use due to significant nephrotoxicity and neurotoxicity.
Rachna B. Patel +10 more
doaj +1 more source
mSystems, 2019 Multidrug-resistant (MDR) Acinetobacter baumannii has emerged as a very problematic pathogen over the past decades, with a high incidence in nosocomial infections. Discovered in the late 1940s but abandoned in the 1970s, polymyxins (i.e., polymyxin B and
Yan Zhu +5 more
doaj +1 more source
A Universal culture medium for screening polymyxin-resistant gram-negative isolates [PDF]
, 2016 The colistin-containing SuperPolymyxin medium was developed for screening polymyxin-resistant Gram-negative bacteria. It was evaluated with 88 polymyxin- susceptible or polymyxin-resistant cultured Gram-negative isolates.
Jayol, Aurélie +2 more
core +1 more source
Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen +4 more
wiley +1 more source
In Vitro Assessment of the Synergy between Polymyxin B (PMB) and Polymyxin B Nonapeptide (PMBN) and Antibiotics on Biofilms from Diabetic Foot Infections [PDF]
, 2015 Background: The increasing resistance of Gram-negative bacteria isolated from nosocomial infections and chronic wounds, such as diabetic foot ulcers has renewed research interests in the use of polymyxins in the treatment of multidrug resistant ...
Greenwell, P. +5 more
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