Results 121 to 130 of about 11,434 (195)

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

mcr‐Mediated Colistin Resistance in Escherichia coli: A One Health Review of Reported Prevalence Across Human, Animal, Food, and Environmental Sectors

open access: yesPublic Health Challenges, Volume 5, Issue 3, September 2026.
This One Health review maps the global prevalence of mcr‐mediated colistin resistance in Escherichia coli across human, animal, food, and environmental sectors. By tracking datasets across diverse geographic regions, the study highlights critical resistance hotspots, emphasizing the urgent need for integrated cross‐sectoral surveillance to limit global
Ferdous‐Ul‐Haque Joy   +3 more
wiley   +1 more source

Prevalence and Genomic Characterization of mcr‐Positive Enterobacteriaceae in Retail Meat in Thailand Following the Colistin Ban

open access: yesMicrobiology and Immunology, Volume 70, Issue 9, Page 402-415, September 2026.
ABSTRACT This study aimed to investigate the prevalence and characteristics of mcr‐positive Enterobacteriaceae in retail meat in Thailand following the national ban on prophylactic colistin use in food producing animals. A total of 152 meat samples (103 chicken and 49 pork) were collected from supermarkets and open markets between July and September ...
Ahmed Abououf   +7 more
wiley   +1 more source

Induced Dysbiosis Modifies Physiological Responses to Warming in a Temperate Sponge

open access: yesEnvironmental Microbiology, Volume 28, Issue 9, September 2026.
We investigated how microbiome disruption affects the physiological response of the calcareous sponge Rowella lancifera to simulated marine heatwave conditions. Antibiotic‐induced microbiome changes amplified physiological responses to increased temperatures, linking microbial stability to host performance.
Manon Broadribb   +3 more
wiley   +1 more source

Microbiological Quality of Roasted Coffee and Survival Dynamics of Dry‐Inoculated Bacteria During Storage

open access: yesJournal of Food Science, Volume 91, Issue 9, September 2026.
ABSTRACT This study evaluated the microbiological quality of 78 roasted coffee samples commercialized in Brazil, including whole‐bean and ground products, and investigated the survival of bacterial species of food safety importance in roasted ground coffee during storage.
Dionisio Pedro Amorim‐Neto   +6 more
wiley   +1 more source

A Lytic Bacteriophage Cocktail Attenuates Carbapenem‐Resistant Klebsiella pneumoniae–Acinetobacter baumannii Mixed‐Species Biofilms and Reshapes Transcriptional Responses

open access: yesMicrobial Biotechnology, Volume 19, Issue 9, September 2026.
A lytic phage cocktail targeting CRKP–CRAB mixed biofilms was systematically evaluated through in vitro, device‐associated, and in vivo models. Integrated transcriptomic analysis revealed molecular responses underlying biofilm disruption, providing mechanistic insights and experimental evidence supporting phage cocktails as a promising strategy against
Xuefang Ren   +9 more
wiley   +1 more source

Revisiting an ‘old’ antibiotic class polymyxins by drug combination therapy targeting Gram-negative superbugs: Toyyiban perspective

open access: yes, 2019
The Islamic concept of halalan-toyyiban encompasses medicines and pharmaceuticals. Halal pharmaceuticals mean the products are free from any unlawful (haram) constituents while in another aspect, toyyib pharmaceuticals particularly concern on the ...
Mahamad Maifiah, Mohd Hafidz   +2 more
core  

Mechanistic Investigations of a Novel Lactam Antifungal Agent Against Candida albicans

open access: yesAPMIS, Volume 134, Issue 9, September 2026.
ABSTRACT Candida albicans presents a major, yet underestimated challenge in clinical settings due to its increased resistance to treatment. This study intended to focus on the utility of a novel proprietary lactam molecule, a quorum sensing (QS) inhibitor, against C. albicans. We assessed isolate susceptibility to lactam treatment. In addition, RNA‐Seq
Hafsa Abduljalil   +6 more
wiley   +1 more source

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