Results 101 to 110 of about 10,639 (243)

Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii

open access: yes, 2020
Background:MDR bacteria represent an urgent threat to human health globally. Polymyxins are a last-line therapy against life-threatening Gram-negative ‘superbugs’, including Acinetobacter baumannii.
Jiang, Xukai   +10 more
core   +1 more source

Polymyxin B Intravenous Administration Strategy Guided by Minimum Inhibitory Concentration in Critically Ill Patients With Pulmonary Infection: Insights From PBPK Modeling

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
PBPK/PD modeling and clinical retrospective validation of intravenous polymyxin B in critically ill patients with pulmonary infection. ABSTRACT Intravenous polymyxin B (PMB) is widely used for treating drug‐resistant gram‐negative pneumonia, though its efficacy in pulmonary infections is considered limited.
Shengnan Zhang   +9 more
wiley   +1 more source

Two Cases of Fibrin Membrane‐Induced Pupillary Block Treated With Neodymium‐Doped Yttrium Aluminium Garnet (Nd:YAG) Laser After Cataract Surgery in Dogs

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study evaluates the clinical efficacy of Nd:YAG laser membranotomy in dogs with fibrin membrane‐induced pupillary block (FMPB). Targeted application of the Nd:YAG laser safely disrupts the obstructive pupillary membrane, thereby restoring normal aqueous humour outflow and effectively resolving secondary intraocular pressure (IOP) elevation without
Haerin Yoon   +6 more
wiley   +1 more source

Progress in the Study of Polymyxin Heteroresistance Molecular Mechanisms

open access: yesXiehe Yixue Zazhi
Polymyxins, a class of cyclic peptide antibiotics, have become the last line of defense against gram-negative bacterial infections as the number of multidrug-resistant bacteria continues to rise.
LI Yanbing, ZHOU Menglan, XU Yingchun
doaj   +1 more source

THE RELEASE OF HISTAMINE BY POLYMYXIN B AND POLYMYXIN E [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1955
S R, BUSHBY, A F, GREEN
openaire   +2 more sources

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

open access: yesBJU International, Volume 138, Issue 1, Page 33-44, July 2026.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon   +3 more
wiley   +1 more source

Antibiotics in Veterinary Ophthalmology: Resistance, Stewardship, and Emerging Antibiotic‐Sparing Strategies

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Antimicrobial resistance (AMR) is a growing challenge in veterinary ophthalmology, particularly in cases of bacterial keratitis, where progressive stromal infection can threaten vision and globe integrity within hours to days. This review synthesizes current evidence on pathogen distribution, antimicrobial susceptibility profiles, multidrug ...
Lionel Sebbag, Oren Pe'er
wiley   +1 more source

Topical Mitomycin C Chemotherapy After Surgical Resection of Conjunctival Amelanotic Melanoma in a Dog

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To describe the clinical course and outcome of adjuvant topical mitomycin C (MMC) therapy following incomplete resection of a conjunctival amelanotic melanoma in a dog. Animals Studied A 15‐year‐old spayed‐female Shih Tzu presented with a conjunctival mass in the right eye (OD).
Junyeong Ahn   +4 more
wiley   +1 more source

ROLES OF AEROSOLISED POLYMYXINS FOR THE TREATMENT OF RESPIRATORY TRACT INFECTIONS: A STEP TOWARDS DOSE OPTIMISATION

open access: yes, 2017
Antibiotic resistance is a major global health challenge. Due to the dry antibiotic discovery pipeline, polymyxins are used as the last-line therapy against Gram- negative ‘superbugs’ such as Pseudomonas aeruginosa, Acinetobacter baumannii, and ...
Lin, Yu-Wei
core  

Clinical Features and Surgical Outcomes of Cats With Presumed Primary Lens Instability: A Retrospective Study of 34 Cases (2018–2022)

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective Describe the clinical features, disease progression, and outcomes of presumed primary lens instability (PLI) in cats, and to assess its association with glaucoma. Animals Studied Thirty‐four cats (68 eyes). Procedures Medical records were reviewed for signalment, clinical history, ophthalmic findings, and treatment.
Havi Sarfaty   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy