Results 121 to 130 of about 15,147 (259)

Progress in the Study of Polymyxin Heteroresistance Molecular Mechanisms

open access: yesXiehe Yixue Zazhi
Polymyxins, a class of cyclic peptide antibiotics, have become the last line of defense against gram-negative bacterial infections as the number of multidrug-resistant bacteria continues to rise.
LI Yanbing, ZHOU Menglan, XU Yingchun
doaj   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva   +3 more
wiley   +1 more source

Precise Construction of an Antimicrobial Peptide Targeting Bacterial Cell Membranes Derived From Natural Peptides

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang   +11 more
wiley   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu   +8 more
wiley   +1 more source

Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
Black and violet phosphorus‐based biomaterials exhibit broad‐spectrum antibacterial efficacy in various infections, including bone, skin, ocular, dental, lung, and sepsis cases. Their antibacterial mechanisms include physical disruption, light‐driven effects, targeted drug delivery, and enhanced composite strategies.
Zhuo Dai   +8 more
wiley   +1 more source

Multi Drug Resistant Pseudomonas aeruginosa in a Health Care Setting in Alexandria

open access: yesJournal of High Institute of Public Health, 2010
The emergence of Multi drug resistant Pseudomonas aeruginosa (MDRPA) among intensive care unit (ICU) patients is increasingly recognized as a public health threat worldwide.
Amani Abaza
doaj   +1 more source

Successful Management of Suspected Epstein–Barr Virus‐Associated Hemophagocytic Lymphohistiocytosis in BRAF‐Mutant Cholangiocarcinoma Following Treatment With Immune Checkpoint Inhibitors and BRAF/MEK Inhibitors: A Case Report

open access: yesCancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background The BRAF V600E mutation is a rare genetic alteration in cholangiocarcinoma for which sequential therapy with immune checkpoint inhibitors (ICIs) and BRAF/MEK inhibitors may be effective. However, the full spectrum of adverse events associated with the sequential use of these agents remains unclear. Hemophagocytic lymphohistiocytosis
Akira Shibata   +9 more
wiley   +1 more source

Mutagenic Analysis of ArnD, an Enzyme Essential for Polymyxin Resistance [PDF]

open access: yes, 2012
Cystic Fibrosis (CF) is the most frequently inherited complication among Caucasians today, affecting 30,000 people in the U.S. alone. The major cause of mortality within CF patients is the development of chronic persistent infections by the opportunistic
Wilcox-Snyder, Blake Marleau
core   +2 more sources

POLYMYXIN P, NEW ANTIBIOTICS OF POLYMYXIN GROUP

open access: yesThe Journal of Antibiotics, 1969
Y, Kimura   +4 more
openaire   +3 more sources

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