Results 11 to 20 of about 2,001 (190)

The effect of antibiotics on the T4polynucleotide ligase catalyzed template dependent polymerization of oligodeoxythymidylates [PDF]

open access: bronzeNucleic Acids Research, 1979
The poly(dA) dependent T4 polynucleotide ligase catalyzed polymerization of oligodeoxythymidylates is dependent upon duplex stability. The antibiotics ethidium bromide, netropsin and Hoechst 33258 stabilize the duplex poly(dA) . P(dT)n (n = 6-10) to thermal denaturation.
Bernd W. Kalisch, Johan H. van de Sande
openalex   +5 more sources

Purification of wheat germ RNA ligase. I. Characterization of a ligase-associated 5'-hydroxyl polynucleotide kinase activity. [PDF]

open access: hybridJournal of Biological Chemistry, 1986
An RNA ligase that catalyzes the formation of a 2'-phosphomonoester-3',5'-phosphodiester bond in the presence of ATP and Mg2+ was purified approximately 6000-fold from raw wheat germ. A 5'-hydroxyl polynucleotide kinase activity copurified with RNA ligase through all chromatographic steps.
Leslie Pick, J Hurwitz
openalex   +3 more sources

Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay

open access: yesFrontiers in Genetics, 2014
Base excision repair (BER) is the predominant cellular mechanism by which human cells repair DNA base damage, sites of base loss and DNA single strand breaks of various complexity, that are generated in their thousands in every human cell per day as a ...
Jason Luke Parsons   +1 more
doaj   +1 more source

Studies on the Joining of DNA by Polynucleotide Ligase of Phage T4

open access: closedCold Spring Harbor Symposia on Quantitative Biology, 1968
C C Richardson   +5 more
openalex   +4 more sources

Dependence of the nature of the Holstein polaron motion in a polynucleotide chain subjected to a constant electric field on the initial polaron state and the parameters of the chain [PDF]

open access: yes, 2021
In this work, we consider the motion of a polaron in a polynucleotide Holstein molecular chain in a constant electric field. It is shown that the character of the polaron motion in the chain depends not only on the chosen parameters of the chain, but also on the initial distribution of the charge along the chain.
arxiv   +1 more source

An onset model of mutually catalytic self-replicative systems formed by an assembly of polynucleotides [PDF]

open access: yes, 2023
Self-replicability is the unique attribute observed in all the living organisms and the question how the life was physically initiated could be equivalent to the question how self-replicating informative polymers were formed in the abiotic material world.
arxiv   +1 more source

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