Results 11 to 20 of about 76,419 (179)

Kinetic and structural insights into the requirement of fungal tRNA ligase for a 2'-phosphate end. [PDF]

RNA
Fungal RNA ligase (LIG) is an essential tRNA splicing enzyme that joins 3′-OH,2′-PO4 and 5′-PO4 RNA ends to form a 2′-PO4,3′-5′ phosphodiester splice junction. Sealing entails three divalent cation-dependent adenylate transfer steps.
Ghosh S, Shuman S.
europepmc   +2 more sources

Repair of Alkylated Bacteriophage T4 Deoxyribonucleic Acid by a Mechanism Involving Polynucleotide Ligase [PDF]

Journal of Virology, 1971
Methyl methanesulfate-induced lesions in bacteriophage T4 are repaired primarily by a mechanism involving polynucleotide ligase. Apparently, other recombinational and ultraviolet repair functions aren't involved.
Marian W. Baldy, Barbara Strom, Harris Bernstein   +2 more
openalex   +5 more sources

Role of the DNA ligase III zinc finger in polynucleotide binding and ligation [PDF]

Nucleic Acids Research, 1998
Mammalian DNA ligase III exists as two distinct isoforms denoted alpha and beta. Both forms possess a motif that is homologous to the putative zinc finger present in poly(ADP-ribose) polymerase. Here, the role of this motif in the binding and ligation of nicked DNA and RNA substrates in vitro has been examined in both isoforms.
Rachel L. Taylor
openalex   +4 more sources

Polynucleotide ligase from myeloid and lymphoid tissues. [PDF]

Proceedings of the National Academy of Sciences, 1968
Tomas Lindahl, Gerald M. Edelman
openalex   +5 more sources

Purification of wheat germ RNA ligase. I. Characterization of a ligase-associated 5'-hydroxyl polynucleotide kinase activity. [PDF]

Journal of Biological Chemistry, 1986
An RNA ligase that catalyzes the formation of a 2'-phosphomonoester-3',5'-phosphodiester bond in the presence of ATP and Mg2+ was purified approximately 6000-fold from raw wheat germ. A 5'-hydroxyl polynucleotide kinase activity copurified with RNA ligase through all chromatographic steps.
Leslie Pick, J Hurwitz
openalex   +3 more sources

Two distinct polynucleotide ligases from rat liver [PDF]

FEBS Letters, 1975
Kinji Tsukada, Hirobumi Teraoka, Mari Shimoyachi   +2 more
openaire   +4 more sources

RNA ligase RtcB splices 3′-phosphate and 5′-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3′)pp(5′)G intermediates

Proceedings of the National Academy of Sciences of the United States of America, 2012
Anupam K. Chakravarty, Roman I. Subbotin, Brian T. Chait, Stewart Shuman   +3 more
openalex   +2 more sources

A polynucleotide ligase from polyoma virus-infected mouse cells [PDF]

Biochemical Journal, 1968
P Beard, J. D. Pitts
openalex   +4 more sources

Direct adenylation from 5'-OH-terminated oligonucleotides by a fusion enzyme containing Pfu RNA ligase and T4 polynucleotide kinase. [PDF]

Nucleic Acids Res, 2022
Yang Z, Zhang C, Lian G, Dong S, Song M, Shao H, Wang J, Zhong T, Luo Z, Jin S, Ding C.   +10 more
europepmc   +2 more sources

Natural Allelic Variations in IbCHYR1-IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato. [PDF]

Adv Sci (Weinh)
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Zhang H, Dai Z, Zhang X, Shang M, Gao X, Ma R, Zhao L, Zhang X, Liu Q, Zhai H, Gao S, Zhao N, Cao Q, Li Q, He S.   +14 more
europepmc   +2 more sources