Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay [PDF]
Frontiers in Genetics, 2014 Base excision repair (BER) is the predominant cellular mechanism by which human cells repair DNA base damage, sites of base loss and DNA single strand breaks of various complexity, that are generated in their thousands in every human cell per day as a ...
Jason Luke Parsons +1 more
doaj +3 more sources
Direct adenylation from 5'-OH-terminated oligonucleotides by a fusion enzyme containing Pfu RNA ligase and T4 polynucleotide kinase. [PDF]
Nucleic Acids Res, 2022 Yang Z +10 more
europepmc +2 more sources
Polynucleotide ligase in mouse cells infected by polyoma virus
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972 Abstract 1. The properties of polynucleotide ligase from mouse cells infected with polyoma virus, and from uninfected mouse cells, were studied in order to investigate the possible involvement of ligase in polyoma DNA replication. 2. Two procedures for the assay of polynucleotide ligase were used to detect ligase in extracts of mouse embryo cells ...
Peter Beard
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Polynucleotide ligase from myeloid and lymphoid tissues. [PDF]
Proceedings of the National Academy of Sciences, 1968 T, Lindahl, G M, Edelman
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A polynucleotide ligase from polyoma virus-infected mouse cells [PDF]
Biochemical Journal, 1968 P, Beard, J D, Pitts
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Polynucleotide Ligase Activity in Adenovirus-Infected Human Embryonic Kidney Cell Cultures
Experimental Biology and Medicine, 1970 SummaryCell-free extracts prepared from human embryonic kidney (HEK) cultures after infection with adenovirus 2 or 12 had a decreased ability to repair single-strand breaks in the HEK cell DNA substrate. The apparent loss of polynucleotide ligase activity found in infected cells may be related to the adenovirus-induced inhibition of HEK cell DNA ...
Nada Ledinko
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Journal of Biological Chemistry, 1986 An RNA ligase that catalyzes the formation of a 2'-phosphomonoester-3',5'-phosphodiester bond in the presence of ATP and Mg2+ was purified approximately 6000-fold from raw wheat germ. A 5'-hydroxyl polynucleotide kinase activity copurified with RNA ligase through all chromatographic steps.
L, Pick, J, Hurwitz
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Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases. [PDF]
Proc Natl Acad Sci U S A, 1994 Shuman S, Liu Y, Schwer B.
europepmc +3 more sources
Natural Allelic Variations in IbCHYR1-IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato. [PDF]
Adv Sci (Weinh)FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Zhang H +14 more
europepmc +2 more sources
Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4 [PDF]
, 2006 The genome of bacteriophage T4 encodes three polynucleotide ligases, which seal the backbone of nucleic acids during infection of host bacteria. The T4Dnl (T4 DNA ligase) and two RNA ligases [T4Rnl1 (T4 RNA ligase 1) and T4Rnl2] join a diverse array of ...
Amitsur +61 more
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