CvfA protein and polynucleotide phosphorylase act in an opposing manner to regulate Staphylococcus aureus virulence. [PDF]
Numata S +4 more
europepmc +3 more sources
The discovery of the mechanisms of biological synthesis of nucleic acids: 1959 Nobel laureates S. Ochoa and A. Kornberg [PDF]
Alongside the chemical and physical research of nucleic acids in the 1940s-50s, the mechanisms of their biosynthesis were investigated. Thus, in 1959, Severo Ochoa and Arthur Kornberg were awarded the Nobel Prize in Physiology or Medicine for the ...
O. P. Matyshevska +2 more
doaj +1 more source
Studies on Polynucleotides Synthesized by Polynucleotide Phosphorylase
Priscilla J. Ortiz, Severo Ochoa
openaire +2 more sources
Regulation of miRNA content. Part 2. Degradation of miRNAs
The scientific review presents the process of regulation of microRNA content — microRNA degradation. To write the article, information was searched using databases Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The ...
A.E. Abaturov, V.L. Babуch
doaj +1 more source
Isolate Specific Cold Response of Yersinia enterocolitica in Transcriptional, Proteomic, and Membrane Physiological Changes [PDF]
Yersinia enterocolitica, a zoonotic foodborne pathogen, is able to withstand low temperatures. This psychrotrophic ability allows it to multiply in food stored in refrigerators. However, little is known about the Y. enterocolitica cold response.
Alter, Thomas +4 more
core +1 more source
Mitochondrial DNA is a target of HBV integration
Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, the role of HBV integration in hepatocellular carcinoma (HCC) development remains unclear.
Domenico Giosa +14 more
doaj +1 more source
8-Oxo-7,8-dihydroguanine (8-oxoG) is a major RNA modification caused by oxidative stresses and has been implicated in carcinogenesis, neurodegeneration, and aging.
Runhua Han +3 more
doaj +1 more source
Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt +37 more
core +2 more sources
New functions for endoribonuclease III were unravelled in the facultative photosynthetic bacterium Rhodobacter sphaeroides by transcriptome analysis and phenotypic screening under three different growth conditions. The RNase III deficient mutant showed reduced pigmentation, linked to decreased expression of photosynthesis‐related mRNAs (bch and crt ...
Janek Börner +2 more
wiley +1 more source
Polynucleotide Phosphorylase from a Cyanobacterium (Synechococcus sp.): Subunit Composition and Properties [PDF]
Polynucleotide phosphorylase from cells of the cyanobacterium Synechococcus sp. has been purified 1400-fold by an improved procedure. The enzyme purified to homogeneity and lacking nuclease, phosphatase and protease contaminations reveals a single band ...
Nolden, W.-T., Richter, G.
core +2 more sources

