Results 31 to 40 of about 6,571 (231)

The discovery of the mechanisms of biological synthesis of nucleic acids: 1959 Nobel laureates S. Ochoa and A. Kornberg [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
Alongside the chemical and physical research of nucleic acids in the 1940s-50s, the mechanisms of their biosynthesis were investigated. Thus, in 1959, Severo Ochoa and Arthur Kornberg were awarded the Nobel Prize in Physiology or Medicine for the ...
O. P. Matyshevska   +2 more
doaj   +1 more source

Studies on Polynucleotides Synthesized by Polynucleotide Phosphorylase

open access: hybridJournal of Biological Chemistry, 1959
Priscilla J. Ortiz, Severo Ochoa
openaire   +2 more sources

Regulation of miRNA content. Part 2. Degradation of miRNAs

open access: yesZdorovʹe Rebenka, 2021
The scientific review presents the process of regulation of microRNA content — microRNA degradation. To write the article, information was searched using databases Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The ...
A.E. Abaturov, V.L. Babуch
doaj   +1 more source

Isolate Specific Cold Response of Yersinia enterocolitica in Transcriptional, Proteomic, and Membrane Physiological Changes [PDF]

open access: yes, 2020
Yersinia enterocolitica, a zoonotic foodborne pathogen, is able to withstand low temperatures. This psychrotrophic ability allows it to multiply in food stored in refrigerators. However, little is known about the Y. enterocolitica cold response.
Alter, Thomas   +4 more
core   +1 more source

Mitochondrial DNA is a target of HBV integration

open access: yesCommunications Biology, 2023
Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, the role of HBV integration in hepatocellular carcinoma (HCC) development remains unclear.
Domenico Giosa   +14 more
doaj   +1 more source

PNPase and RhlB Interact and Reduce the Cellular Availability of Oxidized RNA in Deinococcus radiodurans

open access: yesMicrobiology Spectrum, 2022
8-Oxo-7,8-dihydroguanine (8-oxoG) is a major RNA modification caused by oxidative stresses and has been implicated in carcinogenesis, neurodegeneration, and aging.
Runhua Han   +3 more
doaj   +1 more source

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]

open access: yes, 2009
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt   +37 more
core   +2 more sources

RNase III participates in control of quorum sensing, pigmentation and oxidative stress resistance in Rhodobacter sphaeroides

open access: yesMolecular Microbiology, Volume 120, Issue 6, Page 874-892, December 2023., 2023
New functions for endoribonuclease III were unravelled in the facultative photosynthetic bacterium Rhodobacter sphaeroides by transcriptome analysis and phenotypic screening under three different growth conditions. The RNase III deficient mutant showed reduced pigmentation, linked to decreased expression of photosynthesis‐related mRNAs (bch and crt ...
Janek Börner   +2 more
wiley   +1 more source

Polynucleotide Phosphorylase from a Cyanobacterium (Synechococcus sp.): Subunit Composition and Properties [PDF]

open access: yes, 1982
Polynucleotide phosphorylase from cells of the cyanobacterium Synechococcus sp. has been purified 1400-fold by an improved procedure. The enzyme purified to homogeneity and lacking nuclease, phosphatase and protease contaminations reveals a single band ...
Nolden, W.-T., Richter, G.
core   +2 more sources

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