Results 11 to 20 of about 6,571 (231)

Polynucleotide phosphorylase regulates multiple virulence factors and the stabilities of small RNAs RsmY/Z in Pseudomonas aeruginosa [PDF]

Frontiers in Microbiology, 2016
Post-transcriptional regulation enables bacteria to quickly response to environmental stresses. Polynucleotide phosphorylase (PNPase), which contains an N-terminal catalytic core and C-terminal RNA binding KH-S1 domains, is involved in RNA processing ...
Ronghao eChen, Yuding eWeng, Feng eZhu, Yongxin eJin, Chang eLiu, XiaoLei ePan, Bin eXia, Zhihui eCheng, Shouguang eJin, Shouguang eJin, Weihui eWu   +10 more
doaj   +2 more sources

The exoribonuclease Polynucleotide Phosphorylase influences the virulence and stress responses of yersiniae and many other pathogens [PDF]

Frontiers in Cellular and Infection Microbiology, 2013
Microbes are incessantly challenged by both biotic and abiotic stressors threatening their existence. Therefore, bacterial pathogens must possess mechanisms to successfully subvert host immune defenses as well as overcome the stress associated with host ...
Jason A. Rosenzweig, Ashok K Chopra
doaj   +2 more sources

Localization of components of the RNA-degrading machine in Bacillus subtilis [PDF]

Frontiers in Microbiology, 2016
In bacteria, the control of mRNA stability is crucial to allow rapid adaptation to changing conditions. In most bacteria, RNA degradation is catalyzed by the RNA degradosome, a protein complex composed of endo- and exoribonucleases, RNA helicases and ...
Nora Cascante-Estepa, Katrin Gunka, Jörg Stülke   +2 more
doaj   +3 more sources

Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly [PDF]

Open Biology, 2012
Polynucleotide phosphorylase (PNPase) is an exoribonuclease that cleaves single-stranded RNA substrates with 3′–5′ directionality and processive behaviour.
Steven W. Hardwick, Tobias Gubbey, Isabelle Hug, Urs Jenal, Ben F. Luisi   +4 more
doaj   +2 more sources

Functions of Conserved Domains of Human Polynucleotide Phosphorylase on RNA Oxidation. [PDF]

Insights Biomed Res, 2019
Malla S, Li Z.
europepmc   +3 more sources

Polynucleotide phosphorylase and RNA helicase CshA cooperate in Bacillus subtilis mRNA decay. [PDF]

RNA Biol, 2021
Ingle S, Chhabra S, Laspina D, Salvo E, Liu B, Bechhofer DH.   +5 more
europepmc   +3 more sources

Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation. [PDF]

Proc Natl Acad Sci U S A
Miller LG, Kim W, Schowe S, Taylor K, Han R, Jain V, Park R, Sherman M, Fang J, Ramirez H, Ellington A, Tamamis P, Resendiz MJE, Zhang YJ, Contreras L.   +14 more
europepmc   +3 more sources

Interaction of Bacillus subtilis Polynucleotide Phosphorylase and RNase Y: STRUCTURAL MAPPING AND EFFECT ON mRNA TURNOVER. [PDF]

J Biol Chem, 2016
Salvo E, Alabi S, Liu B, Schlessinger A, Bechhofer DH.   +4 more
europepmc   +3 more sources

Human polynucleotide phosphorylase in mitochondrial RNA metabolism. [PDF]

Biosci Rep
Bakshi N, Kanavalli M, Nowak KZ, Bandyra KJ.   +3 more
europepmc   +3 more sources

The Protein Interaction of RNA Helicase B (RhlB) and Polynucleotide Phosphorylase (PNPase) Contributes to the Homeostatic Control of Cysteine in Escherichia coli. [PDF]

J Biol Chem, 2015
Tseng YT, Chiou NT, Gogiraju R, Lin-Chao S.   +3 more
europepmc   +2 more sources