Results 21 to 30 of about 16,842 (191)
RNase III-Independent Autogenous Regulation of Escherichia coli Polynucleotide Phosphorylase via Translational Repression. [PDF]
J Bacteriol, 2015 The complex post-transcriptional regulation mechanism of Escherichia coli pnp gene, which encodes the phosphorolytic exoribonuclease polynucleotide phosphorylase (PNPase), involves two endoribonucleases, namely RNase III and RNase E, and PNPase itself ...
Carzaniga T, Dehò G, Briani F.
europepmc +2 more sources
Mitochondrial DNA is a target of HBV integration
Communications Biology, 2023 Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, the role of HBV integration in hepatocellular carcinoma (HCC) development remains unclear.
Domenico Giosa +14 more
doaj +1 more source
Microbiology Spectrum, 2022 8-Oxo-7,8-dihydroguanine (8-oxoG) is a major RNA modification caused by oxidative stresses and has been implicated in carcinogenesis, neurodegeneration, and aging.
Runhua Han +3 more
doaj +1 more source
Molecular Microbiology, Volume 120, Issue 6, Page 874-892, December 2023., 2023 New functions for endoribonuclease III were unravelled in the facultative photosynthetic bacterium Rhodobacter sphaeroides by transcriptome analysis and phenotypic screening under three different growth conditions. The RNase III deficient mutant showed reduced pigmentation, linked to decreased expression of photosynthesis‐related mRNAs (bch and crt ...
Janek Börner +2 more
wiley +1 more source
Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity [PDF]
, 1978 Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core +1 more source
A Novel Pathway of Functional microRNA Uptake and Mitochondria Delivery
Advanced Science, Volume 10, Issue 24, August 25, 2023., 2023 In the presence of serum, microRNAs (miRNAs) spontaneously form ≈110 nm nanoparticles, mediated bycationic proteins. When depleted, miRNA uptake is blocked. Unlike lysosome‐located, nanoparticle‐delivere mechanism are preferentially delivered to mitochondria of recipient cells by PNPT1.
Jiachen Liu +13 more
wiley +1 more source
Polynucleotide phosphorylases from thermophiles [PDF]
A purification procedure was developed for Eschericia coli polynucleotide phosphorylase, and subsequently applied to polynucleotide phosphorylases from Thermus aquaticus and Bacillus stearothermophilus. Preliminary investigations of the catalytic properties of the thermostable polynucleotide phosphorylases were carried out in the hope of effecting the ...
Wood, John N. C.
openaire +2 more sources
How hydrolytic exoribonucleases impact human disease: Two sides of the same story
FEBS Open Bio, Volume 13, Issue 6, Page 957-974, June 2023., 2023 Ribonucleases (or simply RNases) are the enzymes responsible for the processing and degradation of all types of RNAs, having multiple roles in every aspect of RNA metabolism. Here, we review what is known about the involvement of the RNase II/RNB family of 3′–5′ exoribonucleases in human disease.
Susana M. Costa +4 more
wiley +1 more source
CATALYTIC PROPERTIES OF THE EUKARYOTIC EXOSOME [PDF]
, 2010 The eukaryotic exosome complex is built around the backbone of a 9‑subunit ring similar to phosporolytic ribonucleases such as RNase PH and polynucleotide phosphorylase (PNPase).
Séraphin, Bertrand +4 more
core +2 more sources
Microorganisms, 2021 Escherichia coli C is a strong biofilm producer in comparison to E. coli K-12 laboratory strains due to higher expression of the pgaABCD operon encoding the enzymes for the biosynthesis of the extracellular polysaccharide poly-β-1,6-N-acetylglucosamine ...
Thomas Carzaniga +5 more
doaj +1 more source