Dipeptides Containing Pyrene and Modified Photochemically Reactive Tyrosine: Noncovalent and Covalent Binding to Polynucleotides [PDF]
Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben+6 more
doaj +2 more sources
Stochastic Sensing of Polynucleotides Using Patterned Nanopores [PDF]
The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated.
Jack A. Cohen+2 more
doaj +2 more sources
Translocation of structured polynucleotides through nanopores [PDF]
We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic barriers for the translocation process.
Akeson M+20 more
arxiv +3 more sources
On the Lubensky-Nelson model of polymer translocation through nanopores [PDF]
We revisit the one-dimensional stochastic model of Lubensky and Nelson [Biophys. J 77, 1824 (1999)] for the electrically driven translocation of polynucleotides through alpha-hemolysin pores. We show that the model correctly describes two further important properties of the experimentally observed translocation time distributions, namely their spread ...
Akeson+46 more
arxiv +4 more sources
Pulling hairpinned polynucleotide chains: Does base-pair stacking interaction matter? [PDF]
Force-induced structural transitions both in relatively random and in designed single-stranded DNA (ssDNA) chains are studied theoretically. At high salt conditions, ssDNA forms compacted hairpin patterns stabilized by base-pairing and base-pair stacking interactions, and a threshold external force is needed to pull the hairpinned structure into a ...
Haijun Zhou, Moroz J. D., Yang Zhang
arxiv +3 more sources
Driven Polymer Translocation Through a Narrow Pore [PDF]
Motivated by experiments in which a polynucleotide is driven through a proteinaceous pore by an electric field, we study the diffusive motion of a polymer threaded through a narrow channel with which it may have strong interactions. We show that there is a range of polymer lengths in which the system is approximately translationally invariant, and we ...
Lubensky, David K., Nelson, David R.
arxiv +5 more sources
An Innovative Lip Boosting Technique Using Polynucleotides: “4-point Cannula Technique” [PDF]
Summary:. The new concept in aesthetic medicine is heading toward regenerative medicine and the use of skin boosters in our practice, so the present case report aimed to evaluate the efficacy of injecting a polynucleotide into the lips for lip ...
Noury Adel, MSc
doaj +2 more sources
Polynucleotides HPT for Asian Skin Regeneration and Rejuvenation [PDF]
Ting Song Lim,1 ShaoRong Liew,1 Xiang Jie Tee,1 Ian Chong,1 Fui Jun Lo,1 Meng Jun Ho,1 KuokTjun Ong,1 Maurizio Cavallini2 1Clique Clinic, Petaling Jaya, Selangor, Malaysia; 2Dermatology and Dermatosurgery Department, CDI Centro Diagnostico Italiano ...
Lim TS+7 more
doaj +2 more sources
Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme [PDF]
Two novel conjugate molecules were designed: pyrene and phenanthridine-amino acid units with a different linker length between the aromatic fragments. Molecular modelling combined with spectrophotometric experiments revealed that in neutral and acidic ...
Josipa Matić+8 more
doaj +2 more sources
Results of Shoulder Adhesive Capsulitis Treatment With the Use of Platelet Rich Plasma and Nucleotide Drugs: A Comparative Study [PDF]
Background. Intra-articular injections of autologous platelet-rich plasma (PRP), which is a natural biological stimulant and affects various parts of the regenerative process, are often used in the treatment of adhesive capsulitis.
Alexey V. Lychagin+3 more
doaj +1 more source