Results 11 to 20 of about 21,167 (270)

Topical natural-origin polynucleotides in radiation-induced skin and mucosal toxicity [PDF]

open access: yesFolia Medica, 2022
Seventy to 90 percent of patients who have received radiation treatment struggle with radiation skin and mucosal toxicity. The inflicted damage to progenitor cells and local microcirculation makes it more likely that wounds, infections, and fibrosis may ...
Stefania Giudici   +5 more
doaj   +3 more sources

Non-Covalent Binding of Tripeptides-Containing Tryptophan to Polynucleotides and Photochemical Deamination of Modified Tyrosine to Quinone Methide Leading to Covalent Attachment

open access: yesMolecules, 2021
A series of tripeptides TrpTrpPhe (1), TrpTrpTyr (2), and TrpTrpTyr[CH2N(CH3)2] (3) were synthesized, and their photophysical properties and non-covalent binding to polynucleotides were investigated.
Antonija Erben   +4 more
doaj   +1 more source

A Biomimetic Polynucleotides–Hyaluronic Acid Hydrogel Promotes Wound Healing in a Primary Gingival Fibroblast Model

open access: yesApplied Sciences, 2021
Polynucleotides (PN) have long been known as an effective supportive therapy for wound healing. The present study investigated whether a hydrogel formulation containing PN and hyaluronic acid (PN + HA) could promote wound healing in an in vitro model of ...
Maria Teresa Colangelo   +4 more
doaj   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

open access: yesCancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin   +6 more
wiley   +1 more source

Bullous striae distensae in a young patient with cardiomyopathy

open access: yesDermatology Reports, 2023
Striae distensae (SD), also known as stretch marks, are observable linear scars that appear where dermal damage has occurred as a result of prolonged stretching of the skin. The actual pathophysiology of SD is still up for debate because its origins are
Yazeed Alowairdhi   +2 more
doaj   +1 more source

A Biomimetic Polynucleotides–Hyaluronic Acid Hydrogel Promotes the Growth of 3D Spheroid Cultures of Gingival Fibroblasts

open access: yesApplied Sciences, 2023
(1) Background: Three-dimensional cultures are useful tools to evaluate regenerative approaches in vitro, as they may mimic the spatial arrangement of cells more closely to natural tissues than routine 2D culture methods. (2) Methods: We investigated the
Maria Teresa Colangelo   +5 more
doaj   +1 more source

Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples. [PDF]

open access: yesPLoS ONE, 2017
Obtaining informative short tandem repeat (STR) profiles from degraded DNA samples is a challenging task usually undermined by locus or allele dropouts and peak-high imbalances observed in capillary electrophoresis (CE) electropherograms, especially for ...
Martín E Mautner   +5 more
doaj   +1 more source

Polydeoxyribonucleotides Pre-Clinical Findings in Bone Healing: A Scoping Review

open access: yesDentistry Journal, 2023
Aim: Polydeoxyribonucleotide (PDRN) is a chain-like polymer derived from DNA. Recent in vitro and animal studies have showcased the beneficial impacts of PDRN on the process of bone mending, whether used on its own or in conjunction with other substances
Mattia Manfredini   +5 more
doaj   +1 more source

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