Results 11 to 20 of about 27,712 (217)

Combined Treatment with Polynucleotides and Hyaluronic Acid Improves Tissue Repair in Experimental Colitis

open access: yesBiomedicines, 2020
Inflammatory bowel diseases (IBDs) are chronic conditions that can benefit from the combined treatment of adenosine receptor agonists and hyaluronic acid (HA), which, binding the CD44, has pro-survival effects.
Giovanni Pallio   +9 more
doaj   +2 more sources

Origin of the Genetic Code Is Found at the Transition between a Thioester World of Peptides and the Phosphoester World of Polynucleotides

open access: yesLife, 2019
The early metabolism arising in a Thioester world gave rise to amino acids and their simple peptides. The catalytic activity of these early simple peptides became instrumental in the transition from Thioester World to a Phosphate World.
Hyman Hartman, Temple F. Smith
doaj   +2 more sources

Stochastic Sensing of Polynucleotides Using Patterned Nanopores [PDF]

open access: yesPhysical Review X, 2012
The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated.
Jack A. Cohen   +2 more
doaj   +2 more sources

Current practices and perceived effectiveness of polynucleotides for treatment of facial erythema by cosmetic physicians. [PDF]

open access: yesSkin Res Technol, 2023
Polynucleotides (PN) are increasingly used for the treatment of facial erythema in the Republic of Korea. However, there are limited pre‐clinical and clinical data on the efficacy of polynucleotides for facial erythema. In this study, we investigated the
Lee D   +10 more
europepmc   +2 more sources

Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. [PDF]

open access: yesInt J Mol Sci
Polynucleotides, complex molecules composed of nucleotides, have gained attention in aesthetic medicine for their potential to regulate gene expression and promote tissue regeneration.
Lee KWA   +6 more
europepmc   +2 more sources

A Biomimetic Polynucleotides–Hyaluronic Acid Hydrogel Promotes the Growth of 3D Spheroid Cultures of Gingival Fibroblasts

open access: yesApplied Sciences, 2023
(1) Background: Three-dimensional cultures are useful tools to evaluate regenerative approaches in vitro, as they may mimic the spatial arrangement of cells more closely to natural tissues than routine 2D culture methods. (2) Methods: We investigated the
Maria Teresa Colangelo   +5 more
doaj   +1 more source

Bullous striae distensae in a young patient with cardiomyopathy

open access: yesDermatology Reports, 2023
Striae distensae (SD), also known as stretch marks, are observable linear scars that appear where dermal damage has occurred as a result of prolonged stretching of the skin. The actual pathophysiology of SD is still up for debate because its origins are
Yazeed Alowairdhi   +2 more
doaj   +1 more source

Consensus report on the use of PN‐HPT™ (polynucleotides highly purified technology) in aesthetic medicine

open access: yesJournal of Cosmetic Dermatology, 2020
Injective procedures using polynucleotides‐based products to promote dermal rejuvenation and revitalization are steadily evolving, yet no structured protocols are available that discuss and provide guidance in aesthetic treatments with highly purified ...
M. Cavallini   +7 more
semanticscholar   +1 more source

L, D-Polydeoxyribonucleotides to provide an essential inhibitory effect on DNA polymerase β of human myeloid leukemia HL60 cells

open access: yesBiochemistry and Biophysics Reports, 2020
The inhibitory effect of D and L-polynucleotides of a given length (40-50n) on the catalytic activity of DNA polymerase β isolated from chromatin cells of acute myeloid leukemia HL-60 was evaluated. The synthesized L enantiomer was found to have a higher
S.V. Stovbun   +5 more
doaj   +1 more source

Fast microwave heating-based one-step synthesis of DNA and RNA modified gold nanoparticles

open access: yesNature Communications, 2022
Simple methods for attaching polynucleotides to gold nanoparticles are of interest for simplifying conjugation in a range of applications. Here, the authors report a microwave heating-based method for the fast, one-step attachment of a range of thiolated
Mengqi Huang   +8 more
doaj   +1 more source

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