Results 21 to 30 of about 22,699 (249)

Nucleic acid vibrational circular dichroism, absorption, and linear dichroism spectra. I. A DeVoe theory approach [PDF]

open access: yes, 1997
Infrared (IR) vibrational circular dichroism (VCD), absorption, and linear dichroism (LD) spectra of four homopolyribonucleotides, poly(rA), poly(rG), poly(rC), and poly(rU), have been calculated, in the 1750–1550 cm-1 spectral region, using the DeVoe ...
Self, B.D., Moore, D.S.
core   +1 more source

Dry/Wet Cycling and the Thermodynamics and Kinetics of Prebiotic Polymer Synthesis

open access: yesLife, 2016
The endoergic nature of protein and nucleic acid assembly in aqueous media presents two questions that are fundamental to the understanding of life’s origins: (i) how did the polymers arise in an aqueous prebiotic world; and (ii) once formed in some ...
David S. Ross, David Deamer
doaj   +1 more source

Error Propagation in the Hypercycle [PDF]

open access: yes, 1999
We study analytically the steady-state regime of a network of n error-prone self-replicating templates forming an asymmetric hypercycle and its error tail.
Campos, P. R. A.   +2 more
core   +2 more sources

Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan

open access: yesScientific Reports, 2017
The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability.
Jia-Wei Shen   +5 more
doaj   +1 more source

Raman depolarization ratios in RNA and DNA are sensitive for sugar-base coupling [PDF]

open access: yes, 1995
Polarized and depolarized Raman spectra are obtained for a number of synthetic polynucleotides containing adenine, uracil, and thymine bases. The depolarization ratios are determined by two methods: (1) by dividing the -spectrum by the -spectrum and (2 ...
Benevides   +17 more
core   +3 more sources

Fast microwave heating-based one-step synthesis of DNA and RNA modified gold nanoparticles

open access: yesNature Communications, 2022
Simple methods for attaching polynucleotides to gold nanoparticles are of interest for simplifying conjugation in a range of applications. Here, the authors report a microwave heating-based method for the fast, one-step attachment of a range of thiolated
Mengqi Huang   +8 more
doaj   +1 more source

Quality Control and Regulatory Scientific Research on Collagen-Based Medical Devices. [PDF]

open access: yesCell Prolif
Cell Proliferation, Volume 59, Issue 1, January 2026.
Wang R, Shi J, Zhou J, Ke L, Yue C.
europepmc   +2 more sources

A Raman spectroscopic study of the interaction between nucleotides and the DNA binding protein gp32 of bacteriophage T4 [PDF]

open access: yes, 1987
Raman spectra of the bacteriophage T4 denaturing protein gp32, its complex with the polynucleotides poly(rA), poly(dA), poly(dT), poly(rU), and poly(rC), and with the oligonucleotides (dA)8 and (dA)2, were recorded and interpreted.
Greve, J., Mul, F.F.M. de, Otto, C.
core   +2 more sources

Non-enzymatic oligonucleotide ligation in coacervate protocells sustains compartment-content coupling

open access: yesNature Communications, 2023
Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content, chemical reactions, and chassis in synthetic compartments represents a key step to the assembly
Tommaso P. Fraccia, Nicolas Martin
doaj   +1 more source

Intra-articular injections of polynucleotides for joint preconditioning before the injections of bionic cross-link hyaluronic acid. Case report [PDF]

open access: yesТерапевтический архив
The article discusses intra-articular injections of polynucleotides (PN) for joint preconditioning before the injections of high-molecular-weight hyaluronic acid (HA) in the context of treating osteoarthritis (OA).
Irina S. Svintsitskaya   +2 more
doaj   +1 more source

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