Results 21 to 30 of about 11,439 (158)
Molecules, 2023 Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben +6 more
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Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies [PDF]
, 2016 Live-cell imaging has provided the life sciences with insights into the cell biology and dynamics. Fluorescent labeling of target molecules proves to be indispensable in this regard. In this Review, we focus on the current fluorescent labeling strategies
Rombouts, Koen +2 more
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Nucleic acid vibrational circular dichroism, absorption, and linear dichroism spectra. I. A DeVoe theory approach [PDF]
, 1997 Infrared (IR) vibrational circular dichroism (VCD), absorption, and linear dichroism (LD) spectra of four homopolyribonucleotides, poly(rA), poly(rG), poly(rC), and poly(rU), have been calculated, in the 1750–1550 cm-1 spectral region, using the DeVoe ...
Self, B.D., Moore, D.S.
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Dry/Wet Cycling and the Thermodynamics and Kinetics of Prebiotic Polymer Synthesis
Life, 2016 The endoergic nature of protein and nucleic acid assembly in aqueous media presents two questions that are fundamental to the understanding of life’s origins: (i) how did the polymers arise in an aqueous prebiotic world; and (ii) once formed in some ...
David S. Ross, David Deamer
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Error Propagation in the Hypercycle [PDF]
, 1999 We study analytically the steady-state regime of a network of n error-prone self-replicating templates forming an asymmetric hypercycle and its error tail.
Campos, P. R. A. +2 more
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Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan
Scientific Reports, 2017 The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability.
Jia-Wei Shen +5 more
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Regulation of metabolism by miR-378 [PDF]
, 2014 The present invention provides a method of regulating fatty acid metabolism in a cell by contacting the cell with a modulator of miR-378 and/or miR-378* activity or expression.
Carrer, Michele, Olson, Eric N.
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Fast microwave heating-based one-step synthesis of DNA and RNA modified gold nanoparticles
Nature Communications, 2022 Simple methods for attaching polynucleotides to gold nanoparticles are of interest for simplifying conjugation in a range of applications. Here, the authors report a microwave heating-based method for the fast, one-step attachment of a range of thiolated
Mengqi Huang +8 more
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A Raman spectroscopic study of the interaction between nucleotides and the DNA binding protein gp32 of bacteriophage T4 [PDF]
, 1987 Raman spectra of the bacteriophage T4 denaturing protein gp32, its complex with the polynucleotides poly(rA), poly(dA), poly(dT), poly(rU), and poly(rC), and with the oligonucleotides (dA)8 and (dA)2, were recorded and interpreted.
Greve, J., Mul, F.F.M. de, Otto, C.
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Nature Communications, 2023 Modern cells are complex chemical compartments tightly regulated by an underlying DNA-encoded program. Achieving a form of coupling between molecular content, chemical reactions, and chassis in synthetic compartments represents a key step to the assembly
Tommaso P. Fraccia, Nicolas Martin
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