Raman depolarization ratios in RNA and DNA are sensitive for sugar-base coupling [PDF]
, 1995 Polarized and depolarized Raman spectra are obtained for a number of synthetic polynucleotides containing adenine, uracil, and thymine bases. The depolarization ratios are determined by two methods: (1) by dividing the -spectrum by the -spectrum and (2 ...
Benevides +17 more
core +3 more sources
Interaction and Binding Modes of bis-Ruthenium(II) Complex to Synthetic DNAs
Metals, 2016 [μ-(linker)L2(dipyrido[3,2-a:2′,3′-c]phenazine)2(phenanthroline)2Ru(II)2]2+ with linker: 1,3-bis-(4-pyridyl)-propane, L: PF6 (bis-Ru-bpp) was synthesized and their binding properties to a various polynucleotides were investigated by spectroscopy ...
Hasi Rani Barai +3 more
doaj +1 more source
DNA Renaturation at the Water-Phenol Interface [PDF]
, 2003 We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
121 +161 more
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Nucleotides: Structure and Properties [PDF]
, 2005 Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core +1 more source
Angewandte Chemie, EarlyView.Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai +5 more
wiley +2 more sources
Carbethoxylation of Polynucleotides [PDF]
European Journal of Biochemistry, 1971 Diethyl pyrocarbonate has been shown to react with poly(A), poly(C) and poly(G) but poly(U) does not react. Diethyl pyrocarbonate appears to carbethoxylate amino groups on the bases. Poly(A) can bind one carbethoxy group per base but the binding capacity of poly(G) and poly(C) under non‐denaturing conditions is 0.32 and 0.23, respectively.
openaire +2 more sources
INTRAARTICULAR KNEE JOINT INJECTION: HYALURONIC ACID VS POLYNUCLEOTIDES [PDF]
Euromediterranean Biomedical Journal, 2013 This study is a retrospective work of ambulatorial injections in patients suffering from Class II osteoarthritis (OA) of the knee. The research was conducted from January 2012 to July 2012 in a private clinic in Benevento, Hospital Val D'Elsa ...
Luigi Meccariello
doaj +1 more source
Intra-articular injections of polynucleotides for joint preconditioning before the injections of bionic cross-link hyaluronic acid. Case report [PDF]
Терапевтический архивThe article discusses intra-articular injections of polynucleotides (PN) for joint preconditioning before the injections of high-molecular-weight hyaluronic acid (HA) in the context of treating osteoarthritis (OA).
Irina S. Svintsitskaya +2 more
doaj +1 more source
Prebiotic selection for motifs in a model of template-free elongation of polymers within compartments. [PDF]
PLoS ONE, 2017 The transition from prelife where self-replication does not occur, to life which exhibits self-replication and evolution, has been a subject of interest for many decades. Membranes, forming compartments, seem to be a critical component of this transition
Grant Kinsler +3 more
doaj +1 more source
Covalent binding studies on the 14C-labeled antitumour compound 2,5-bis(1-aziridinyl)-1,4-benzoquinone. Involvement of semiquinone radical in binding to DNA, and binding to proteins and bacterial macromolecules in situ [PDF]
, 1990 2,5-Bis(1-aziridinyl)-1,4-benzoquinone (BABQ) is a compound from which several antitumour drugs are derived, such as Trenimone, Carboquone and Diaziquone (AZQ).
Egberink, Richard J.M. +5 more
core +2 more sources