Results 41 to 50 of about 27,712 (217)

Hyaluronate Increases Polynucleotides Effect on Human Cultured Fibroblasts

, 2013
The HA is present in almost all vertebrates and plays a critical role in tissue development and cell proliferation, it has been demonstrated to promote wound healing and involved in angiogenesis and inflammation.
S. Guizzardi, J. Uggeri, S. Belletti, G. Cattarini   +3 more
semanticscholar   +1 more source

Natural Allelic Variations in IbCHYR1–IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato

Advanced Science, EarlyView.
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang, Zhuoru Dai, Xiaochen Zhang, Meiqi Shang, Xiaoru Gao, Ruiqi Ma, Limeng Zhao, Xiaoli Zhang, Qingchang Liu, Hong Zhai, Shaopei Gao, Ning Zhao, Qinghe Cao, Qiang Li, Shaozhen He   +14 more
wiley   +1 more source

A Two‐Component Pseudo‐Icosahedral Protein Nanocompartment with Variable Shell Composition and Irregular Tiling

Advanced Science, EarlyView.
The structure and assembly principles of a two‐component encapsulin nanocompartment shell are reported. The two‐component protein compartment self‐assembles from two distinct HK97‐fold shell proteins into a pseudo‐icosahedral protein shell with variable composition and irregular tiling.
Cassandra A. Dutcher, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

Fluorimetric and CD Recognition between Various ds-DNA/RNA Depends on a Cyanine Connectivity in Cyanine-guanidiniocarbonyl-pyrrole Conjugate

Molecules, 2020
Two novel isosteric conjugates of guanidiniocarbonyl-pyrrole and 6-bromo-TO (thiazole orange) were prepared, differing only in linker connectivity to cyanine (benzothiazole nitrogen vs. quinoline nitrogen).
Tamara Šmidlehner, Marta Košćak, Ksenija Božinović, Dragomira Majhen, Carsten Schmuck, Ivo Piantanida   +5 more
doaj   +1 more source

Advances in Fabricating the Electrospun Biopolymer-Based Biomaterials

Journal of Functional Biomaterials, 2021
Biopolymers formed into a fibrous morphology through electrospinning are of increasing interest in the field of biomedicine due to their intrinsic biocompatibility and biodegradability and their ability to be biomimetic to various fibrous structures ...
Sebastian Wilk, Aleksandra Benko
doaj   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

A Review of Recent Developments in Biopolymer Nano-Based Drug Delivery Systems with Antioxidative Properties: Insights into the Last Five Years

Pharmaceutics
In recent years, biopolymer-based nano-drug delivery systems with antioxidative properties have gained significant attention in the field of pharmaceutical research. These systems offer promising strategies for targeted and controlled drug delivery while
Magdalena Stevanović, Nenad Filipović
doaj   +1 more source

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids

Journal of Experimental Medicine, 1981
Hybridomas the produce anti-DNA autoantibodies were prepared from spleen cells of unimmunized MRL/1 mice, a strain that spontaneously develops severe systemic lupus erythematous (SLE).
E. Lafer, J. Rauch, C. Andrzejewski, David R. Mudd, B. Furie, B. Furie, R. Schwartz, B. Stollar   +7 more
semanticscholar   +1 more source

Biologically‐oriented alveolar ridge preservation to correct bone dehiscence at immediate implant placement

Clinical Advances in Periodontics, EarlyView.
Abstract Background The purpose of the present case study is to describe the application of a modification of the Biologically‐oriented Alveolar Ridge Preservation (BARP) principles in cases of peri‐implant bone dehiscence (PIBD) due to a compromised alveolus at immediate implant placement (IIP).
Leonardo Trombelli, Tommaso Grenzi
wiley   +1 more source

Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

BMC Musculoskeletal Disorders, 2021
Background A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might improve knee function and joint pain
Cesare Stagni, Martina Rocchi, Alessandro Mazzotta, Nicolandrea Del Piccolo, Nicola Rani, Marco Govoni, Leonardo Vivarelli, Francesca Veronesi, Milena Fini, Dante Dallari   +9 more
doaj   +1 more source