Results 71 to 80 of about 27,614 (213)
Driven Polymer Translocation Through a Narrow Pore [PDF]
, 1999 Motivated by experiments in which a polynucleotide is driven through a proteinaceous pore by an electric field, we study the diffusive motion of a polymer threaded through a narrow channel with which it may have strong interactions. We show that there is a range of polymer lengths in which the system is approximately translationally invariant, and we ...
arxiv +1 more source
Molecules, 2012 We report herein the synthesis and characterization of 9-(2-diallylaminoethyl) adenine. We evaluated two different synthetic routes starting with adenine where the optimal route was achieved through coupling of 9-(2-chloroethyl)adenine with diallylamine.
Karyn Usher +4 more
doaj +1 more source
Nucleic Acids Research, 1998 The computer molecular modeling program HINT (Hydropathic INTeractions), an empirical hydropathic force field function that includes hydrogen bonding, coulombic and hydrophobic terms, was used to study sequence-selective doxorubicin binding/intercalation
Glen E. Kellogg +2 more
semanticscholar +1 more source
Beilstein Journal of Organic Chemistry, 2020 Two novel unnatural amino acids, prepared by linking a dicationic purple-coloured and fluorescent naphthalene diimide (NDI) at core position to amino acid side chains of variable length, strongly interacted with ds-DNA/RNA by threading intercalation ...
Annike Weißenstein +3 more
doaj +1 more source
Scientia Pharmaceutica, 2019 Thio- and cyano- modified single-stranded poly(dNTP) sequences of different molecular sizes (20−200 n) and the same lengths routine poly(dNTP) and poly(NTP) species were tested for their impact on catalytic activities of β-like DNA polymerases
Sergey Stovbun +4 more
doaj +1 more source
European Journal of Biochemistry, 1995 The endeavour to enhance gene therapy has led to increased research on the development of simple, efficient and safe delivery systems. This study deals with the use of an artificial cationic lipid on the encapsulation of genetic material in liposomes ...
C. Puyal +3 more
semanticscholar +1 more source
Lipids contribute to epigenetic control via chromatin structure and functions
ScienceOpen Research, 2015 Isolated cases of experimental evidence over the last few decades have shown that, where specifically tested, both prokaryotes and eukaryotes have specific lipid molecules bound to nucleoproteins of the genome.
Renad Zhdanov +6 more
doaj +1 more source
CHIMIA, 1974 Owing to a suitable enzymatic equipment the living cell synthesizes macromolecular chains (proteins, nucleic acids, polysaccharides) which can be considered as condensation products of the corresponding difunctionnal monomers (amino acids, nucleotides ...
C. Sadron, A. Brack, G. Spach
doaj +1 more source
Solvable models of neighbor-dependent nucleotide substitution processes [PDF]
arXiv, 2005 We prove that a wide class of models of Markov neighbor-dependent substitution processes on the integer line is solvable. This class contains some models of nucleotide substitutions recently introduced and studied empirically by molecular biologists. We show that the polynucleotide frequencies at equilibrium solve explicit finite-size linear systems ...
arxiv
AIP AdvancesThe mesoscopic irreversible thermodynamic treatment of α-polypeptides and the helical polynucleotides (DNA) furnishes two sets of analytical expressions, which allow us not only to analyze the reversible force–extension experiments performed by atomic ...
Tarik Omer Ogurtani
doaj +1 more source