Results 71 to 80 of about 38,341 (274)
Mg2+ ion effect on stability of double-stranded popynucleotide formed by polyriboinosinic and polyribocytidilic chains [PDF]
Biophysical Bulletin, 2, 68, 2005 (in russian), 2020 Mg2+ effect on the thermal stability of the double-stranded polynucleotide polyIpolyC (IC) under conditions close to physiological ones (0.1M Na+, pH7) was studied by the differential UV spectroscopy. The initial increase of the ion concentration ([Mg2+]) leads to the increase of the melting temperature (Tm) and to the decrease of the absorption ...
arxiv
Complexation of DNA with Cationic Surfactant [PDF]
, 1999 Transfection of an anionic polynucleotide through a negatively charged membrane is an important problem in genetic engineering. The direct association of cationic surfactant to DNA decreases the effective negative charge of the nucleic acid, allowing the DNA-surfactant complex to approach a negatively charged membrane.
arxiv +1 more source
Stacking and Hydrogen Bonding. DNA Cooperativity at Melting [PDF]
Biopolymers 75, 434 (2004), 2004 By taking into account base-base stacking interactions we improve the Generalized Model of Polypeptide Chain (GMPC). Based on a one-dimensional Potts-like model with many-particle interactions, the GMPC describes the helix-coil transition in both polypeptides and polynucleotides.
arxiv +1 more source
Clinical Advances in Periodontics, EarlyView.Abstract Background The purpose of the present case study is to describe the application of a modification of the Biologically‐oriented Alveolar Ridge Preservation (BARP) principles in cases of peri‐implant bone dehiscence (PIBD) due to a compromised alveolus at immediate implant placement (IIP).
Leonardo Trombelli, Tommaso Grenzi
wiley +1 more source
PharmaceuticsIn recent years, biopolymer-based nano-drug delivery systems with antioxidative properties have gained significant attention in the field of pharmaceutical research. These systems offer promising strategies for targeted and controlled drug delivery while
Magdalena Stevanović, Nenad Filipović
doaj +1 more source
Torsion and bending of nucleic acids studied by subnanosecond time-resolved fluorescence depolarization of intercalated dyes [PDF]
, 1982 Subnanosecond time‐resolved fluorescence depolarization has been used to monitor the reorientation of ethidium bromide intercalated in native DNA, synthetic polynucleotide complexes, and in supercoiled plasmid DNA.
Millar, D. P. +2 more
core
Binding of Carminomycin to synthetic polyribonucleotides poly(A) and poly(U): absorption and polarized fluorescence study [PDF]
Biophysical Bulletin 488(1)(2000)56-59.(in Ukrainian), 2020 Binding of anthracycline antibiotic carminomycin (CM) to synthetic polyribonucleotides poly(A) and poly(U) was studied in solution of low ionic strength in a wide phosphate-to-dye (P/D) range using absorption and polarized fluorescence spectroscopy. Two different modes of CM binding to the ss-polynucleotides have been identified.
arxiv
Role of the particle's stepping cycle in an asymmetric exclusion process: A model of mRNA translation [PDF]
Phys. Rev. E 81, 051904 (2010), 2009 Messenger RNA translation is often studied by means of statistical-mechanical models based on the Asymmetric Simple Exclusion Process (ASEP), which considers hopping particles (the ribosomes) on a lattice (the polynucleotide chain). In this work we extend this class of models and consider the two fundamental steps of the ribosome's biochemical cycle ...
arxiv +1 more source
ChemBioChem, Volume 26, Issue 8, April 14, 2025.Some neurodegenerative disorders can be driven by recurrent mutations in the C9orf72 gene. These sequences can fold into G‐quadruplex secondary structures. Here, by performing in silico investigations coupled with FRET DNA melting assays, we unraveled the molecular basis for the selectivity of a series of organic and organometallic C9orf72 G4‐binders ...
Luisa D'Anna +9 more
wiley +1 more source
A Gibbs approach to Chargaff's second parity rule [PDF]
J. Statist. Phys. 146(2), 408-422, 2012, 2011 Chargaff's second parity rule (CSPR) asserts that the frequencies of short polynucleotide chains are the same as those of the complementary reversed chains. Up to now, this hypothesis has only been observed empirically and there is currently no explanation for its presence in DNA strands.
arxiv +1 more source