A Novel Virus Detected in Papillomas and Carcinomas of the Endangered Western Barred Bandicoot ( Perameles bougainville ) Exhibits Genomic Features of both the Papillomaviridae and Polyomaviridae [PDF]
Journal of Virology, 2007 ABSTRACT Conservation efforts to prevent the extinction of the endangered western barred bandicoot ( Perameles bougainville ) are currently hindered by a progressively debilitating cutaneous and mucocutaneous papillomatosis and carcinomatosis syndrome observed in captive and
Woolford, L. +9 more
openaire +3 more sources
Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination
Viruses, 2020 Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj +1 more source
Survey of KI, WU, MW and STL polyomavirus in cancerous and non-cancerous lung tissues [PDF]
, 2018 K
Bidiga, László +4 more
core +1 more source
Evidence for a Structural Relationship between BRCT Domains and the Helicase Domains of the Replication Initiators Encoded by thePolyomaviridaeandPapillomaviridaeFamilies of DNA Tumor Viruses [PDF]
Journal of Virology, 2008 ABSTRACTStudies of DNA tumor viruses have provided important insights into fundamental cellular processes and oncogenic transformation. They have revealed, for example, that upon expression of virally encoded proteins, cellular pathways involved in DNA repair and cell cycle control are disrupted.
Anuradha, Kumar +5 more
openaire +2 more sources
Comparative analysis of the extent of protein–protein interactions in icosahedral viral capsids
Protein Science, Volume 34, Issue 9, September 2025.Abstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Noah J. Zimmerman +2 more
wiley +1 more source
Role of BK human polyomavirus in cancer
Infectious Agents and Cancer, 2018 Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date.
Jorge Levican +4 more
doaj +1 more source
MISSEL: a method to identify a large number of small species-specific genomic subsequences and its application to viruses classification [PDF]
, 2016 Continuous improvements in next generation sequencing technologies led to ever-increasing collections of genomic sequences, which have not been easily characterized by biologists, and whose analysis requires huge computational effort.
Babakir Mina, Muhammed +10 more
core +2 more sources
Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System
Advanced Science, Volume 12, Issue 25, July 3, 2025.This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao +7 more
wiley +1 more source
The Influence of Oncogenic Viruses in Renal Carcinogenesis: Pros and Cons
Pathogens, 2022 Viral infections are major contributors to the global cancer burden. Recent advances have revealed that known oncogenic viruses promote carcinogenesis through shared host cell targets and pathways.
Bianca Manole +8 more
doaj +1 more source
Journal of Medical Virology, Volume 97, Issue 2, February 2025.ABSTRACT To date, no drugs are approved for BK polyomavirus (BKPyV) reactivation, a major cause of nephropathy after kidney transplantation. Recently, tumor necrosis factor‐α (TNF‐α) blockade has been proposed as a promising therapy, however, the effect of TNF‐α on the clinically most common archetype (ww) BKPyV remained unclear.
Lise Lauterbach‐Rivière +20 more
wiley +1 more source