Results 91 to 100 of about 3,093 (195)

Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton [PDF]

open access: yes, 2018
Viruses have a dual nature: particles are “passive substances” lacking chemical energy transformation, whereas infected cells are “active substances” turning-over energy.
Burckhardt, CJ   +3 more
core   +2 more sources

Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier   +4 more
wiley   +1 more source

Viruses in unexplained encephalitis cases in American black bears (Ursus americanus).

open access: yesPLoS ONE, 2020
Viral infections were investigated in American black bears (Ursus americanus) from Nevada and northern California with and without idiopathic encephalitis.
Charles E Alex   +12 more
doaj   +1 more source

Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth

open access: yesViruses, 2020
Merkel cell polyomavirus (MCV) is the only known human oncogenic virus in the polyomaviridae family and the etiological agent of most Merkel cell carcinomas (MCC).
Nnenna Nwogu   +2 more
doaj   +1 more source

Cell entry strategies of animal viruses [PDF]

open access: yes, 2018
Virusi su obligatni unutarstanični paraziti građeni od nukleinske kiseline (DNA ili RNA) i proteinske kapside, dok je lipidna ovojnica, koju neki virusi posjeduju, porijeklom od domaćinske stanice.
Čolić, Daniel
core   +2 more sources

A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene [PDF]

open access: yes, 2006
Background Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses.
Larry A Hanson   +3 more
core   +1 more source

Merkel Cell Polyomavirus—Pathophysiology and Treatment in the Era of Gene‐Targeted Therapies

open access: yesReviews in Medical Virology, Volume 34, Issue 5, September 2024.
ABSTRACT Merkel cell polyomavirus (MCPyV) is a significant contributor to the development of Merkel cell carcinoma (MCC), an aggressive skin cancer with high recurrence and a low survival rate. In fact, it is the deadliest skin cancer. The precise routes of transmission for MCPyV‐positive MCC remain unclear, but several factors may trigger its ...
Trairong Chokwassanasakulkit   +1 more
wiley   +1 more source

DNA and seroprevalence study of MW and STL polyomaviruses

open access: yesJournal of Medical Virology, Volume 96, Issue 8, August 2024.
Abstract The clinical importance and the pathogenesis of the MW and STL polyomaviruses (PyVs) remain unclear. Our aim was to study the seroprevalence of MWPyV and STLPyV, and to examine the prevalence of viral DNA in respiratory samples and secondary lymphoid tissues. In total, 618 serum samples (0.8–90 years) were analyzed for seroprevalence.
Melinda Katona   +3 more
wiley   +1 more source

A viral metagenomic survey identifies known and novel mammalian viruses in bats from Saudi Arabia.

open access: yesPLoS ONE, 2019
Bats are implicated as natural reservoirs for a wide range of zoonotic viruses including SARS and MERS coronaviruses, Ebola, Marburg, Nipah, Hendra, Rabies and other lyssaviruses.
Nischay Mishra   +15 more
doaj   +1 more source

Receptor-Binding and Oncogenic Properties of Polyoma Viruses Isolated from Feral Mice [PDF]

open access: yes, 2011
Laboratory strains of the mouse polyoma virus differ markedly in their abilities to replicate and induce tumors in newborn mice. Major determinants of pathogenicity lie in the sialic binding pocket of the major capsid protein Vp1 and dictate receptor ...
Benjamin, Thomas L.   +7 more
core   +1 more source

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