Journal of Medical Virology, Volume 96, Issue 3, March 2024.Abstract Quantification of Torque teno virus (TTV) load emerged as a marker of immunosuppression. Associations of TTV load with complications and survival after allogeneic hematopoietic cell transplantation (allo‐HCT) were controversial in published studies. In this prospective study, we aimed to identify factors influencing TTV load after allo‐HCT and
Micha Srour +5 more
wiley +1 more source
The interplay between viral-derived miRNAs and host immunity during infection [PDF]
, 2019 MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad +3 more
core +1 more source
Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells [PDF]
, 2005 Cancer immunotherapy has been extensively attempted by gene transfer of cytokines with viral vectors. In this work, we compared the therapeutic effects of interleukin 12 and 15 (IL-12 and IL-15) genes transferred to tumor cells or to dendritic cells (DCs)
Fortes, P. (Puri) +5 more
core +1 more source
Protein Science, Volume 33, Issue 2, February 2024.Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Emily M. Cross +10 more
wiley +1 more source
Possible antiviral effect of ciprofloxacin treatment on polyomavirus BK replication and analysis of non-coding control region sequences [PDF]
, 2013 Acute renal dysfunction (ARD) is a common complication in renal transplant recipients. Multiple factors contribute to ARD development, including acute rejection and microbial infections.
Anna Bellizzi +8 more
core +1 more source
Metastatic Squamous Cell Carcinoma in a Northern Brown Bandicoot (Isoodon macrourus) [PDF]
, 2017 Aside from a handful of notable exceptions, neoplasia is not reported as a major cause of mortality in wild animal populations and often goes undetected.
Beck, Amanda P. +3 more
core +3 more sources
The gut virome:the ‘missing link’ between gut bacteria and host immunity? [PDF]
, 2019 The human gut virome includes a diverse collection of viruses that infect our own cells as well as other commensal organisms, directly impacting on our well-being. Despite its predominance, the virome remains one of the least understood components of the
Carding, Simon R. +4 more
core +2 more sources
Metagenomic sequencing for surveillance of food- and waterborne viral diseases [PDF]
, 2017 A plethora of viruses can be transmitted by the food- and waterborne route. However, their recognition is challenging because of the variety of viruses, heterogeneity of symptoms, the lack of awareness of clinicians, and limited surveillance efforts ...
Koopmans D.V.M., M.P.G. (Marion) +1 more
core +3 more sources
Whole Genome Sequencing of KI Polyomavirus Strain from Patient with Breast Cancer in Basrah City [PDF]
Journal of Bioscience and Applied ResearchBackground: Polyomaviruses are small, circular, non-enveloped viruses with a diameter of about 40–50 nm, and have a double-stranded DNA molecule descended from the Polyomaviridae. 32 PyV strains are described, more than 10 of which are reported to infect
akeel Alabadi +2 more
doaj +1 more source
Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication [PDF]
, 2015 License:Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)Background: The human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein.
Barbara van Loon +9 more
core +2 more sources