Results 101 to 110 of about 3,093 (195)
Human polyomaviruses and cancer: an overview
Clinics, 2018 The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado +5 more
doaj +1 more source
Characterization of a novel polyomavirus isolated from a fibroma on the trunk of an African elephant (Loxodonta africana). [PDF]
PLoS ONE, 2013 Viruses of the family Polyomaviridae infect a wide variety of avian and mammalian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction.
Hans Stevens +4 more
doaj +1 more source
Skin Research and Technology, Volume 30, Issue 8, August 2024.Abstract Background As a common chronic recurrent inflammatory skin disease, psoriasis is characterized by erythema and scaly skin lesions, with infection as an integral part of the pathogenesis of many diseases. Many previous cases reported the impact of psoriasis on infection.
Minghui Lu +5 more
wiley +1 more source
Polyomavirus T antigens activate an antiviral state [PDF]
, 2014 The large T antigen (TAg) of the polyomavirus Simian virus 40 (SV40) is known to play an important role in several events during the viral life cycle, including DNA replication, transcription, and virion assembly.
Giacobbi, Nicholas
core
Hybrid organic-inorganic nanoparticles: controlled incorporation of gold nanoparticles into virus-like particles and application in surface-enhanced Raman spectroscopy. [PDF]
, 2007 A capsid is the protein coat surrounding a virus' genome that ensures its protection and transport. The capsid of murine polyomavirus (muPy) consists of one major (VP1) and two minor (VP2/3) proteins, from which just VP1 is sufficient to form the capsid ...
Ferguson, Charles +7 more
core +1 more source
Journal of Medical Virology, Volume 96, Issue 7, July 2024.Abstract Merkel cell carcinoma (MCC) is a highly aggressive skin cancer associated with integration of Merkel cell polyomavirus (MCPyV). MCPyV‐encoded T‐antigens (TAs) are pivotal for sustaining MCC's oncogenic phenotype, i.e., repression of TAs results in reactivation of the RB pathway and subsequent cell cycle arrest. However, the MCC cell line LoKe,
Kuan Cheok Lei +11 more
wiley +1 more source
Factors influencing the production of recombinant SV40 vectors [PDF]
, 2004 Most gene therapy approaches employ viral vectors for gene delivery. Ideally, these vectors should be produced at high titer and purity with well-established protocols.
Fortes, P. (Puri) +3 more
core +1 more source
Journal of Medical Virology, Volume 96, Issue 6, June 2024.Abstract Polyomaviruses BK (BKPyV) and JC (JCPyV), belonging to the Polyomaviridae, are responsible for human pathologies. In kidney transplant recipients, BKPyV replication can lead to irreversible nephron damage whereas JCPyV replication remains asymptomatic.
Baptiste Demey +8 more
wiley +1 more source
Diversity and Evolution of Viral Pathogen Community in Cave Nectar Bats (Eonycteris spelaea)
Viruses, 2019 Bats are unique mammals, exhibit distinctive life history traits and have unique immunological approaches to suppression of viral diseases upon infection.
Ian H Mendenhall +7 more
doaj +1 more source
Commentary on the Regulation of Viral Proteins in Autophagy Process [PDF]
, 2014 The ability to subvert intracellular antiviral defenses is necessary for virus to survive as its replication occurs only in the host cells. Viruses have to modulate cellular processes and antiviral mechanisms to their own advantage during the entire ...
Cheng, Ching-Yuan +2 more
core +3 more sources