Results 61 to 70 of about 21,637 (166)
Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley +1 more source
BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy
BK polyomavirus (BKPyV) infection is a common asymptomatic viral infection in the general population. Severe complications are seen in immunocompromised individuals, such as polyomavirus-associated nephropathy (PyVAN) in renal transplant recipients. Information on BKPyV microRNA expressions is scarce, although polyomavirus-encoded microRNAs have been ...
Virtanen, Elina +8 more
openaire +3 more sources
ABSTRACT Background Among the many forms of cancer that plague women all over the globe, breast cancer (BC) is one of the most prevalent kinds. BC is a multifaceted disease that can manifest in many ways depending on the individual. Aims The identification of new biomarkers that may be used to diagnose and prognosis of the BC, as well as those that can
Ramin Moeini +2 more
wiley +1 more source
Glycosphingolipids as Receptors for Non-Enveloped Viruses
Glycosphingolipids are ubiquitous molecules composed of a lipid and a carbohydrate moiety. Their main functions are as antigen/toxin receptors, in cell adhesion/recognition processes, or initiation/modulation of signal transduction pathways.
Stefan Taube +2 more
doaj +1 more source
ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley +1 more source
We have seen the re-emergence of a virus, normally latent in the urinary tract, which becomes activated in renal transplant patients due to potent immunosuppression. Polyomavirus reactivates within the allograft kidney, causing renal dysfunction and graft loss in 40 to70% of patients with overt renal dysfunction and histologically proven Polyomavirus ...
Emilio, Ramos, Cinthia, Drachenberg
openaire +1 more source
Organ Transplantation: Current Status, Challenges, and Future Prospects
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
Novel polyomavirus in the endangered garden dormouse Eliomys quercinus
Background The garden dormouse (Eliomys quercinus) has experienced a significant population decline across Europe in recent decades. While habitat loss and climate change are often cited as primary factors, pathogen exposure, either to novel or to ...
Emilija Vasiliūnaitė +7 more
doaj +1 more source
Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro +2 more
wiley +1 more source
Frequency of JC Virus Appearance in the Urine of Post-Transplantation Patients
Polyomaviruses are common viruses that induce various infections in many mammalian species, including humans. The best-known viruses of this kind are BKV and JCV.
Boguszewska Anastazja +3 more
doaj +1 more source

