Results 91 to 100 of about 19,303 (227)

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta, Nikolaos Salaris, Ashish Kalkal, Fernando Yuen Chang, Maryam Javed, Azhar Ali Khan, Priya Mandal, Stavroula Balabani, Reza Motallebzadeh, Manish K. Tiwari   +9 more
wiley   +1 more source

Mouse polyomavirus infection induces lamin reorganisation

The FEBS Journal
The nuclear lamina is a dense network of intermediate filaments beneath the inner nuclear membrane. Composed of A‐type lamins (lamin A/C) and B‐type lamins (lamins B1 and B2), the nuclear lamina provides a scaffold for the nuclear envelope and chromatin, thereby maintaining the structural integrity of the nucleus.
Kateřina Bruštíková, Boris Ryabchenko, Sandra Žáčková, Vojtěch Šroller, Jitka Forstová, Lenka Horníková   +5 more
openaire   +4 more sources

Full‐House Nephropathy Without Lupus Manifesting During Acute Kidney Allograft Rejection: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley   +1 more source

Pre-Transplantation Assessment of BK Virus Serostatus: Significance, Current Methods, and Obstacles

Viruses, 2019
The immunosuppression required for graft tolerance in kidney transplant patients can trigger latent BK polyomavirus (BKPyV) reactivation, and the infection can progress to nephropathy and graft rejection.
Fatima Dakroub, Antoine Touzé, Haidar Akl, Etienne Brochot   +3 more
doaj   +1 more source

Organ Transplantation: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Possible antiviral effect of ciprofloxacin treatment on polyomavirus BK replication and analysis of non-coding control region sequences [PDF]

, 2013
Acute renal dysfunction (ARD) is a common complication in renal transplant recipients. Multiple factors contribute to ARD development, including acute rejection and microbial infections.
Anna Bellizzi, Anna Mitterhofer, Assunta Zavatto, Carlo Mancini, Donatella Rodio, Elena Anzivino, Francesca Tinti, Ilaria Umbro, Valeria Pietropaolo   +8 more
core   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, Volume 293, Issue 2, Page 325-347, January 2026.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy

International Journal of Organ Transplantation Medicine, 2015
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat, R Yaghobi, Z Salmanpoor, J Roozbeh, S Torabinezhad, S Kadkhodaei   +5 more
doaj  

A Retrograde Trafficking Inhibitor of Ricin and Shiga-Like Toxins Inhibits Infection of Cells by Human and Monkey Polyomaviruses

mBio, 2013
Polyomaviruses are ubiquitous pathogens that cause severe disease in immunocompromised individuals. JC polyomavirus (JCPyV) is the causative agent of the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML), whereas BK ...
Christian D. S. Nelson, Dan W. Carney, Aaron Derdowski, Alex Lipovsky, Gretchen V. Gee, Bethany O’Hara, Paul Williard, Daniel DiMaio, Jason K. Sello, Walter J. Atwood   +9 more
doaj   +1 more source