Results 71 to 80 of about 19,515 (224)

Human polyomavirus infection: Cytological and molecular diagnosis [PDF]

open access: yesRevista da Associação Médica Brasileira, 2017
Summary Few studies directly compare urinary cytology with molecular methods for detecting BK and JC polyomaviruses. Reactivation of BKV infection is the main risk factor for the development of nephropathy in immunocompromised individuals. The limitation of the cytological method can be attributed to the stage where the infected cell does not have ...
Assis, Patricia Gioia de   +1 more
openaire   +4 more sources

SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG

open access: yesEuropean Journal of Immunology, Volume 56, Issue 5, May 2026.
IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė   +3 more
wiley   +1 more source

Avian polyomavirus: a recent update [PDF]

open access: yes, 2017
Avian polyomavirus disease is among the most common viral diseases of domesticated exotic birds as such in psittacine families. Caused by avian polyomavirus (APV) which possess a circular, double-stranded DNA which encodes for major structural virus ...
Abdul Razak, Mariatulqabtiah   +2 more
core  

MISSEL: a method to identify a large number of small species-specific genomic subsequences and its application to viruses classification [PDF]

open access: yes, 2016
Continuous improvements in next generation sequencing technologies led to ever-increasing collections of genomic sequences, which have not been easily characterized by biologists, and whose analysis requires huge computational effort.
Babakir Mina, Muhammed   +10 more
core   +2 more sources

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Polyomavirus – an emergent pathogen in transplant recipients [PDF]

open access: yesEinstein (São Paulo), 2007
Medical centers that work with transplants often face opportunisticinfections that demand specific tools to make diagnosis. Theprevalence of latent polyomavirus infections is high, and the mostcommon site of latency of the most prevalent polyomavirus in ...
Juliana de Moura Montagner   +8 more
doaj  

Clinical metagenomics. [PDF]

open access: yes, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core  

An Accurate Genetic Colocalisation Method for the HLA Locus

open access: yesHLA, Volume 107, Issue 5, May 2026.
ABSTRACT Genetic colocalisation analyses are frequently conducted to determine if causal signals at a genetic locus are shared between two phenotypes. However, colocalisation is rarely undertaken at the HLA locus, due to its complex linkage disequilibrium (LD) and high polymorphism density.
Guillaume Butler‐Laporte   +18 more
wiley   +1 more source

High frequency of JCV DNA detection in prostate cancer tissues [PDF]

open access: yes, 2015
BACKGROUND: Prostate cancer (PC) represents the most frequently diagnosed cancer in men. Exposure to infectious agents has been considered to induce prostatic inflammation and cancerous transformation.
Anzivino, Elena   +7 more
core  

Review on the role of the human Polyomavirus JC in the development of tumors [PDF]

open access: yes, 2017
Almost one fifth of human cancers worldwide are associated with infectious agents, either bacteria or viruses, and this makes the possible association between infections and tumors a relevant research issue.
Manola Comar   +2 more
core   +1 more source

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