Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen +7 more
wiley +1 more source
Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat +5 more
doaj
Progressive multifocal leukoencephalopathy (PML) is a severely debilitating and often fatal demyelinating disease of the central nervous system (CNS) in immunosuppressed individuals caused by JC polyomavirus (JCV), a ubiquitous human pathogen ...
Aron eLukacher, Elizabeth eFrost
doaj +1 more source
Droplet Digital CRISPR for Nucleic Acid Detection
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang +4 more
wiley +1 more source
BK POLYOMAVIRUS-INFECTED DECOY CELLS IN URINE CYTOLOGY SPECIMENS OF RENAL TRANSPLANT RECIPIENTS
Background:BK polyomavirus is one of the common post-transplant viral infections, affecting ?15% of renal transplantation recipients (RTR), leading to graft loss in more than half of cases.
Asmaa B. Al-Obaidi +6 more
doaj +4 more sources
Vírus causadores de câncer e o papel da medicina laboratorial: revisão de literatura e perspectivas [PDF]
Cancer-causing viruses are responsible for up to 20% of cancers with infectious etiology, representing a serious public health problem worldwide. Since the discovery of the first human cancer-causing virus, several others have been associated with ...
Granato, Celso Francisco Hernandes +1 more
core +3 more sources
BK virus‐associated urothelial carcinoma—A supra‐regional cohort of kidney transplant recipients
Abstract Objectives This study aims to study the clinical features, pathological findings, and outcomes of BK virus‐associated urothelial carcinoma (UC) in kidney transplant recipients (KTRs). Patients and Methods The study was conducted in a retrospective cohort of KTRs with histologically confirmed UC managed at a UK supra‐regional transplant urology
Noah Beetge +4 more
wiley +1 more source
Pre-Transplantation Assessment of BK Virus Serostatus: Significance, Current Methods, and Obstacles
The immunosuppression required for graft tolerance in kidney transplant patients can trigger latent BK polyomavirus (BKPyV) reactivation, and the infection can progress to nephropathy and graft rejection.
Fatima Dakroub +3 more
doaj +1 more source
Human polyomaviruses in children undergoing transplantation, United States, 2008-2010 [PDF]
Immunocompromised patients are at risk for disease caused by infection by some polyomaviruses. To define the prevalence of polyomaviruses in children undergoing transplantation, we collected samples from a longitudinal cohort and tested for the 9 known ...
Bauer, Irma +11 more
core +2 more sources

