Results 31 to 40 of about 20,275 (199)

Aurkin-A, a TPX2-Aurora A small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressive diffuse large B cell lymphoma

open access: yesNeoplasia: An International Journal for Oncology Research
Chemotherapy induced polyploidy is a mechanism of inherited drug resistance resulting in an aggressive disease course in cancer patients. Alisertib, an Aurora Kinase A (AK-A) ATP site inhibitor, induces cell cycle disruption resulting in polyaneuploidy ...
Patrick J. Conway   +6 more
doaj   +1 more source

Drivers of insect herbivory resistance and tolerance to plant damage in the Brachypodium distachyon species complex

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Insect herbivory is a major biotic factor shaping plant populations and driving the evolution of defensive traits. Polyploidy (whole‐genome duplication) often induces substantial phenotypic and genotypic changes that may affect species interactions, including herbivory.
Antonio J. Manzaneda   +4 more
wiley   +1 more source

Realization of Lodging Tolerance in the Aromatic Grass, Cymbopogon khasianus Through Ploidy Intervention

open access: yesFrontiers in Plant Science, 2022
Artificial polyploidy that brings about increase in cell size confers changes in histo-morphology leading to altered phenotype, causing changes in physiological attributes and enhanced concentration of secondary metabolites.
Yerramilli Vimala   +5 more
doaj   +1 more source

Shaped by context: Evolutionary trajectories of desiccation tolerance in land plants

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Desiccation tolerance (DT), the ability to survive near‐complete cellular dehydration, is widespread in diaspores but rare in the vegetative tissues of land plants. The patchy and punctuated phylogenetic distribution of vegetative desiccation tolerance (VDT) suggests that the trait is both ancient and recurrent, yet the evolutionary ...
Rose A. Marks   +2 more
wiley   +1 more source

Focus on polyploidy [PDF]

open access: yesNew Phytologist, 2010
Polyploidy (whole-genome duplication) has played a pervasive role in the evolution of fungi and animals, and is particularly prominent in plants (Wendel & Doyle, 2005; Cui et al., 2006; Otto, 2007; Wood et al., 2009). This important evolutionary phenomenon has attracted renewed and growing interest from the scientific community in the last decade since
Aïnouche, Malika L., Jenczewski, Eric
openaire   +5 more sources

The spread of non‐native species

open access: yesBiological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock   +16 more
wiley   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Morphological Characterization of Tetraploids of Limonium sinuatum (L.) Mill. Produced by Oryzalin Treatment of Seeds

open access: yesHorticulturae, 2021
Limonium sinuatum (L.) Mill. (2n = 2x = 16) is a popular ornamental plant with dimorphism of pollen grains (type A and type B) and stigmas (papilla and cob-like).
Shiro Mori   +10 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Polyploidy [PDF]

open access: yesJournal of Experimental Biology, 1924
ABSTRACT By polyploidy is meant an increase in the number of sets of chromosomes in a plant or animal. The bodies of animals and of the higher plants normally contain two sets of chromosomes, one derived from each parent. In ordinary sexual reproduction this number is reduced to one half in the maturation of the germ cells, and the ...
openaire   +1 more source

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