Results 71 to 80 of about 1,853 (164)

Biological biomarkers of oral cancer

Periodontology 2000, Volume 96, Issue 1, Page 250-280, October 2024.
Abstract The oral squamous cell carcinoma (OSCC) 5 year survival rate of 41% has marginally improved in the last few years, with less than a 1% improvement per year from 2005 to 2017, with higher survival rates when detected at early stages. Based on histopathological grading of oral dysplasia, it is estimated that severe dysplasia has a malignant ...
Allan Radaic, Pachiyappan Kamarajan, Alex Cho, Sandy Wang, Guo‐Chin Hung, Fereshteh Najarzadegan, David T. Wong, Hung Ton‐That, Cun‐Yu Wang, Yvonne L. Kapila   +9 more
wiley   +1 more source

Sequence features of variable region determining physicochemical properties and polyreactivity of therapeutic antibodies [PDF]

, 2019
International audienceTherapeutic antibodies have transformed the clinical practice. Not surprisingly, development of antibody thera-peutics is currently the main focus of the biotechnology industry.
Dimitrov, Jordan, Kanyavuz, Alexia, Lacroix-Desmazes, Sébastien, Lecerf, Maxime,   +3 more
core   +2 more sources

Detection of polyreactive immunoglobulin G facilitates diagnosis in children with autoimmune hepatitis

Hepatology International
Abstract Objective The detection of autoantibodies is essential to diagnose autoimmune hepatitis (AIH). Particularly in children, specificity of autoantibodies decreases due to lower titers being diagnostic and being present not only in AIH but also in other liver diseases.
Engel, Bastian, Diestelhorst, Jana, Hupa-Breier, Katharina Luise, Kirchner, Theresa, Henjes, Nicole, Loges, Stephanie, Yuksel, Muhammed, Janczyk, Wojciech, Lalanne, Claudine, Zachou, Kalliopi, Oo, Ye, Gournay, Jérôme, Pape, Simon, Drenth, Joost, Renand, Amédée, Dalekos, George, Muratori, Luigi, Socha, Piotr, Ma, Yun, Arikan, Cigdem, Baumann, Ulrich, Manns, Michael, Wedemeyer, Heiner, Junge, Norman, Jaeckel, Elmar, Taubert, Richard   +25 more
openaire   +7 more sources

All roads lead to IgA: Mapping the many pathways of IgA induction in the gut

Immunological Reviews, Volume 326, Issue 1, Page 66-82, September 2024.
Summary The increasing prevalence of food allergy and related pathologies in recent years has underscored the need to understand the factors affecting adverse reactions to food. Food allergy is caused when food‐specific IgE triggers the release of histamine from mast cells. However, other food‐specific antibody isotypes exist as well, including IgG and
Emily R. Siniscalco, Adam Williams, Stephanie C. Eisenbarth   +2 more
wiley   +1 more source

Chronic lymphocytic leukemia: insights from lymph nodes & bone marrow and clinical perspectives [Kronična limfocitna leukemija: uvidi iz limfnog čvora i koštane srži i kliničke perspektive] [PDF]

, 2010
B-cell chronic lymphocytic leukemia (B-CLL) is characterized by highly variable distribution of tumor mass between peripheral blood, bone marrow and lymphoid organs which is important for staging, classification and prognosis.
Jakšić, Branimir, Jakšić, Ozren, Kardum-Skelin, Ika   +2 more
core  

Antifungal and antitumor models of bioactive protective peptides [PDF]

, 2009
Peptides are remarkably reactive molecules produced by a great variety of species and able to display a number of functions in uni-and multicellular organisms as mediators, agonists and regulating substances. Some of them exert cytotoxic effects on cells
Dobroff, Andrey Sergee, Rodrigues, Elaine Guadelupe, Taborda, Carlos Pelleschi, Travassos, Luiz Rodolpho   +3 more
core   +3 more sources

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Immunoglobulin E-Mediated Autoimmunity [PDF]

, 2018
The study of autoimmunity mediated by immunoglobulin E (IgE) autoantibodies, which may be termed autoallergy, is in its infancy. It is now recognized that systemic lupus erythematosus, bullous pemphigoid (BP), and chronic urticaria, both spontaneous and ...
Altrichter, Sabine, Church, Martin K., Maurer, Marcus, Metz, Martin, Scheffel, Jörg, Schmetzer, Oliver   +5 more
core   +1 more source

Assessment of total hepatitis C virus (HCV) core protein in HCV-related mixed cryoglobulinemia [PDF]

, 2014
INTRODUCTION: In hepatitis C virus (HCV)-related mixed cryoglobulinemia (MCG), the nonenveloped HCV core protein (HCV-Cp) is a constituent of the characteristic cold-precipitating immune complexes (ICs).
Angela Vinella, Domenico Sansonno, Fabio Pavone, Franco Dammacco, Gianfranco Lauletta, Maria Mariggiò, Sabino Russi, Silvia Sansonno   +7 more
core   +2 more sources

Changing expression of vertebrate immunity genes in an anthropogenic environment: a controlled experiment [PDF]

, 2016
Background: The effect of anthropogenic environments on the function of the vertebrate immune system is a problem of general importance. For example, it relates to the increasing rates of immunologically-based disease in modern human populations and to ...
A Cuesta, A Ledin, A Lesher, AA Margolin, AA Sneddon, AL Filby, AM Trama, AP Devalapalli, B Qu, BFG Manly, CL Andersen, D Haase, D Haase, D Pacitti, DL Cram, DW Dunne, F Gambón-Deza, F Takizawa, FC Jones, G Borkow, G Wang, GA Rook, I Hanski, Ida M. Friberg, IM Friberg, IM Friberg, IM Friberg, J Wang, J Zou, J Zou, JA Beck, JA Jackson, JA Jackson, JA Jackson, JD Biller-Takahashi, JH Steiger, JM Grim, Joseph A. Jackson, L Zhang, LR Machado, M Brown, M Mittal, M Ohtani, M Schartl, Martha Brown, MK Purcell, N Mantel, P Boysen, P Yarahmadi, Pascal I. Hablützel, R Chia, R Jia, R Wang, RI Jennrich, RJ Wootton, SR Abolins, T Boehm, T Sakai, T Takada, TD Williams, TL Lenz, Y Huang, Y Valero, Y Wen, YF Gu   +64 more
core   +3 more sources