Results 131 to 140 of about 23,350 (227)

Distinct Modes of Hidden Structural Dynamics in the Functioning of an Allosteric Polysaccharide Lyase. [PDF]

ACS Cent Sci, 2022
Dash P, Acharya R.
europepmc   +1 more source

Recent Progressions in Applications of Bioactive Polysaccharides in Food and Health Sciences: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine ...
M V N L Chaitanya, Bahjat Alhasso, Wadhah Hasan Alkhazali, Ashok Kumar Bishoyi, Rami Oweis, S. Renuka Jyothi, Rishiv Kalia, Laxmidhar Maharana, Ashish Singh Chauhan, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil, Asghar Narmani, Bagher Farhood   +14 more
wiley   +1 more source

Revisiting Hyaluronan Catabolism in Bacteroides: Pathway Conservation, Overlooked Proteins, and Predictive Accuracy

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Hyaluronan degradation in Bacteroides cannot be reliably predicted from canonical PL8/GH88 enzymes alone. Experimental validation reveals coordinated induction of noncanonical accessory proteins (BT4410/BT4411), highlighting pathway plasticity and context‐dependent glycosaminoglycan utilization. ABSTRACT The ability of gut microbes to degrade host‐ and
Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky, Gabriela Ambrozova, Lukas Kubala, Kristyna Turkova   +6 more
wiley   +1 more source

Structural insights into the mechanism of pH-selective substrate specificity of the polysaccharide lyase Smlt1473. [PDF]

J Biol Chem, 2021
Pandey S, Mahanta P, Berger BW, Acharya R.   +3 more
europepmc   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Structural and functional analysis of gum arabic l-rhamnose-α-1,4-d-glucuronate lyase establishes a novel polysaccharide lyase family. [PDF]

J Biol Chem, 2021
Kondo T, Kichijo M, Maruta A, Nakaya M, Takenaka S, Arakawa T, Fushinobu S, Sakamoto T.   +7 more
europepmc   +1 more source

Exploiting Paraphaeosphaeria minitans and Its Antifungal Metabolites as Bio‐Fungicides for Eco‐Friendly Management of Head Rot Disease in Cabbage

Microbial Biotechnology, Volume 19, Issue 2, February 2026.
Biocontrol of Cabbage Head Rot: Paraphaeosphaeria minitans produces antifungal metabolites, disrupts sclerotia of Sclerotinia sclerotiorum, and reduces disease incidence in cabbage under field conditions. ABSTRACT Cabbage head rot, caused by Sclerotinia sclerotiorum, threatens crop yield and quality.
Meena V. Ruppavalli, Muthusamy Karthikeyan, Iruthayasamy Johnson, Sivaji Jeevanantham, Parthiban V. Kumaresan, Balakrishnan Prithiviraj, Sambasivam Periyannan   +6 more
wiley   +1 more source

Diversity, Function and Activity of DNA Viruses in the Qiangyong Proglacial Lake Sediment, the Tibetan Plateau

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao, Meiling Feng, Hongfei Chi, Keshao Liu, Rong Wen, Weizhen Zhang, Pengfei Liu   +6 more
wiley   +1 more source

Identification and characterization of a critical loop for the high activity of alginate lyase VaAly2 from the PL7_5 subfamily

Frontiers in Microbiology
As the major component in the cell wall of brown algae, alginates are degradable by alginate lyases via β-elimination. Alginate lyases can be categorized into various polysaccharide lyase (PL) families, and PL7 family alginate lyases are the largest ...
Muxuan Du, Muxuan Du, Xue Li, Weipeng Qi, Yingjie Li, Lushan Wang   +5 more
doaj   +1 more source