Results 121 to 130 of about 23,515 (209)

Bacteriophage-encoded depolymerases: their diversity and biotechnological applications [PDF]

open access: yes, 2016
Bacteriophages (phages), natural enemies of bacteria, can encode enzymes able to degrade polymeric substances. These substances can be found in the bacterial cell surface, such as polysaccharides, or are produced by bacteria when they are living in ...
A Abdi-Ali   +112 more
core   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, Volume 45, Issue 3, Page 455-475, May/June 2026.
ABSTRACT Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Unraveling the molecular mechanism of polysaccharide lyases for efficient alginate degradation

open access: yesNature Communications
Alginate lyases (ALs) are essential for breaking down brown macroalgae alginates, widely used naturally-occurring polysaccharides. Their molecular mechanisms remain challenging due to the lack of catalytically competent Michaelis-Menten complex structures.
José Pablo Rivas-Fernández   +12 more
openaire   +4 more sources

Characterisation of High Alkaline-Tolerant Novel Ulvan Lyase from Pseudoalteromonas agarivorans: Potential Applications of Enzyme Derived Oligo-Ulvan as Anti-Diabetic Agent

open access: yesMarine Drugs
Green algae, particularly Ulva species, are rich in complex polysaccharides, such as ulvan, which have significant potential for biotechnological applications. However, the biochemical properties of ulvan depolymerised products remain underexplored.
Navindu Dinara Gajanayaka   +8 more
doaj   +1 more source

Elucidation of the recognition mechanisms for hemicellulose and pectin in Clostridium cellulovorans using intracellular quantitative proteome analysis [PDF]

open access: yes, 2015
Clostridium cellulovorans is an anaerobic, cellulolytic bacterium, capable of effectively degrading and metabolizing various types of substrates, including cellulose, hemicellulose (xylan and galactomannan), and pectin.
Hironobu Morisaka   +4 more
core   +2 more sources

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu   +8 more
wiley   +1 more source

Novel GH115 xylan α‐1,2‐glucuronidases with distinct preferences for xylan‐derived oligomers and polymers

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin‐dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's ...
Savvina Leontakianakou   +9 more
wiley   +1 more source

A nanostructural view of the cell wall disassembly process during fruit ripening and postharvest storage by atomic force microscopy [PDF]

open access: yes, 2018
Background: The mechanical properties of parenchyma cell walls and the strength and extension of adhesion areas between adjacent cells, jointly with cell turgor, are main determinants of firmness of fleshy fruits.
A. Patrick Gunning   +122 more
core   +1 more source

Draft genome of Neofabraea vagabunda, the agent of bull's eye rot

open access: yesAnnals of Applied Biology, Volume 188, Issue 3, Page 941-946, May 2026.
Circular representation of the 12 major scaffolds from the draft genome of Neofabraea vagabunda showing gene density, density of repeated regions, GC content, and functional features (secrete and membrane proteins, proteases, and CAZymes) distribution.
Saveria Mosca   +4 more
wiley   +1 more source

Conformational analysis of the Streptococcus pneumoniae hyaluronate lyase and characterization of Its hyaluronan-specific carbohydrate-binding module

open access: yes, 2014
For a subset of pathogenic microorganisms, including Streptococcus pneumoniae, the recognition and degradation of host hyaluronan contributes to bacterial spreading through the extracellular matrix and enhancing access to host cell surfaces.
Boraston, AB   +7 more
core   +1 more source

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