Alginate lyase (AL) is a polysaccharide-degrading enzyme that can degrade alginate by hydrolyzing glycosidic bonds and produces unsaturated alginate oligosaccharides (AOSs). These AOSs have wide therapeutic and nutraceutical applications.
Simranjeet Kaur +3 more
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Alginate lyases are critical enzymes in hydrolyzing alginate into alginate oligosaccharides (AOS), which are bioactive compounds known for their antioxidant properties and ability to lower serum glucose and lipid concentrations.
Xiaoyan Zhuang +11 more
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Rhamnogalacturonan lyase reveals a unique fold and suggests a common polysaccharide lyase mechanism [PDF]
M. A. McDonough +4 more
openaire +1 more source
Untangling the Reaction Mechanism of the Polysaccharide Lyase PL42 Using QM/MM Metadynamics Simulations. [PDF]
Alonso-Gil S +3 more
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Characterization of a bifunctional alginate lyase as a new member of the polysaccharide lyase family 17 from a marine strain BP-2. [PDF]
Huang G +9 more
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Crystal structure of <i>Vibrio cholerae</i> polysaccharide lyase RbmB bound to <i>Vibrio</i> polysaccharide (VPS) fragments provides insights into substrate recognition and cleavage. [PDF]
Weerasekera R +16 more
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Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel. [PDF]
Loiodice M +18 more
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The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29. [PDF]
Ndeh D +6 more
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Applying a polysaccharide lyase from Stenotrophomonas maltophilia to disrupt alginate exopolysaccharide produced by Pseudomonas aeruginosa clinical isolates. [PDF]
Felton SM +10 more
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The structure of a pectin-active family 1 polysaccharide lyase from the marine bacterium Pseudoalteromonas fuliginea. [PDF]
Hobbs JK, Boraston AB.
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