Results 151 to 160 of about 122,045 (290)

Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double‐blind, randomized controlled DHA‐WIN trial

International Journal of Cancer, EarlyView.
What's New? Omega‐3 docosahexaenoic acid (DHA) has shown pleiotropic anti‐cancer effects both in vitro and in animal models. However, clinical evidence of DHA efficacy is limited. This randomized, double‐blind, placebo‐controlled trial tested the efficacy of supplementation with DHA 4.4 g/day during 18 weeks of breast cancer neoadjuvant chemotherapy ...
Jaqueline Munhoz, Marnie Newell, Gilbert Bigras, Susan Goruk, Anil Abraham Joy, Sunita Ghosh, Kerry S. Courneya, Vera Mazurak, Claire M. Douglas, Xiaofu Zhu, Bohdarianna Zorniak, John Mackey, Judith Meza Junco, Julie Price Hiller, Karen King, Sanraj K. Basi, Catherine J. Field   +16 more
wiley   +1 more source

Metabolomics Approach Revealed Polyunsaturated Fatty Acid Disorders as Pathogenesis for Chronic Pancreatitis-Induced Osteoporosis in Mice. [PDF]

Metabolites
Liu X, Hu F, Zhang Y, Ma S, Liu H, Shang D, Yin P.   +6 more
europepmc   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways. [PDF]

Front Nutr
Jian-Tong, Zhou MT, Song XZ, Yang L, Fang YH, Liu L, Cui JS, Lu XC, Zhu HY, Jin YB, Han HM.   +10 more
europepmc   +1 more source

Plasma Phospholipid Polyunsaturated Fatty Acid Associations with Neurocognition. [PDF]

Nutrients, 2023
Ling J, Keilp JG, Galfalvy HC, Cardino VN, Ahmed A, Burke AK, Fenton JI, Mann JJ, Sublette ME.   +8 more
europepmc   +1 more source

Effect of Various Methods of Epidermal-Dermal Separation on the Distribution of 14C-Acetate-Labeled Polyunsaturated Fatty Acids in Skin Compartments

, 1974
David I. Wilkinson, John Walsh
openalex   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Association Between ω-3, ω-6 Polyunsaturated Fatty Acid and Sleep Disorders: From Cross-Sectional to Mendelian Randomization Studies. [PDF]

Food Sci Nutr
Wang L, Quan W, Song J, Qin Y, Zeng H, Zhang J, Zhao X, Li J, Chen J.   +8 more
europepmc   +1 more source

Alternative route for the biosynthesis of polyunsaturated fatty acids in K562 cells [PDF]

, 1993
Javier Naval, María José Martínez‐Lorenzo, Isabel Marzo, Paula Desportes, Andrés Piňeiro   +4 more
openalex   +1 more source

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

Interdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang, Yufei Yang, Bingxu Chen, Yanmeng Zhao, Haitao Sun   +4 more
wiley   +1 more source