PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis
Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
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The effect of omega-3 Polyunsaturated Fatty Acid (PUFA) prescription preparations on the prevention of clinical cardiovascular disease: a meta-analysis of RCTs. [PDF]
Dong S+8 more
europepmc +1 more source
The aim of this study is to compare oats and rice as the main cereal source of a low‐gluten diet followed by metabolically challenged volunteers. The participants consumed four portions of either oat or rice products daily for 6 weeks and avoided glutinous cereals.
Enni Mannila+9 more
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Relationship Between Serum ω-3 Polyunsaturated Fatty Acid Concentration and Fatty Acid Fraction of Epicardial Adipose Tissue in Patients With Cardiovascular Disease. [PDF]
Fukuda T+10 more
europepmc +1 more source
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela+5 more
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Patterns of perinatal polyunsaturated fatty acid status and associated dietary or candidate-genetic factors. [PDF]
Abou Assi A+8 more
europepmc +1 more source
Acetylcholinesterase Inhibition and Antioxidant Activity of DHA‐Disubstituted Phospholipids
1,2‐Di‐DHA‐PC phospholipids in nutraceutical form may cross the blood‐brain barrier and inhibit acetylcholinesterase (AChE) activity, with an efficacy similar to galantamine. This suggests their potential as neuroprotective agents in the treatment of Alzheimer's disease.
Ernestina Garcia‐Quinto+4 more
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Salt-sensitive hypertension in GR mutant rats is associated with altered plasma polyunsaturated fatty acid levels and aortic vascular reactivity. [PDF]
Verouti S+10 more
europepmc +1 more source
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez+5 more
wiley +1 more source