Results 221 to 230 of about 436,338 (306)

Dietary n-3 Polyunsaturated Fatty Acids From Fish Are Associated With Better Healthy Aging Indicators: Results of the DIAPELH Study. [PDF]

J Hum Nutr Diet
Foscolou A, Pratti T, Detopoulou P, Argyri K, Nikolaou G, Kouskouti A, Malikourti A, Petrogianni M, Shurdha E, Psaroudaki E, Panoutsopoulos GI, Vamvakas S, Gioxari A.   +12 more
europepmc   +1 more source

Incretin and Glucagon Signalling in MASLD and MASH: Integrating Metabolic Pathways With Disease Progression

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) arises from dysregulated interactions between nutrient delivery, adipose tissue lipid handling and liver lipid metabolism, which collectively coalesce to drive inflammatory signalling leading to metabolic dysfunction‐associated steatohepatitis (MASH) and fibrosis. Recent clinical
Evangelia E. Tsakiridis, Gregory R. Steinberg   +1 more
wiley   +1 more source

Advances in Oral Drug Delivery Systems for Natural Polyunsaturated Fatty Acids: Enhancing Bioavailability and Therapeutic Potential. [PDF]

Pharmaceutics
Zazula MF, Pozzan R, Dos Reis GA, Maciel M, Horlem T, Banckes TN, Pereira JLS, Sales-Campos C, Fernandes LC, Martinez-Burgos WJ, Naliwaiko K.   +10 more
europepmc   +1 more source

Flooding affects fluctuating asymmetry but not growth of a riparian orbweaving spider

Ecological Entomology, EarlyView.
In a mesocosm experiment we assessed the impact of flood on aquatic insect emergence and on spider development using geometric morphometric analysis of fluctuating asymmetry. We observed 45% higher emergence in flooded mesocosm throughout the season. Spiders did not grow bigger but exhibited ~15% lower fluctuating asymmetry than in controls.
Stephane Mutel, Martin H. Entling, Ken M. Mauser, Federica Spani, Celia Thomas, Collins Ogbeide, Mirco Bundschuh, Franziska Fiolka, Franziska Middendorf, Ralf Schulz, Alessandro Manfrin   +10 more
wiley   +1 more source

Can Omega-3 polyunsaturated fatty acids improve bone mineral density?: Evidence from a Mendelian randomization study. [PDF]

Medicine (Baltimore)
Gou X, Zhang R, Li M, Xu R, Zhang D, Zhang T.   +5 more
europepmc   +1 more source

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

Widespread but moderate genetic overlap between circulating polyunsaturated fatty acids and brain disorders. [PDF]

J Lipid Res
Xu H, Sun Y, Francis M, Cheng CF, Modulla NTR, Brenna JT, Chiang CWK, Ye K.   +7 more
europepmc   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Pharmaco-nutraceutical improvement of the response to obeticholic acid with omega-3 polyunsaturated fatty acids. [PDF]

Biochem J
Lavoie AA, Thérien A, Silva A, Paré E, Ciešlak A, Gagnon W, Desjardins C, Verreault M, Trottier J, Vohl MC, Drouin-Chartier JP, Corbeil J, Caron A, Barbier O.   +13 more
europepmc   +1 more source