Results 231 to 240 of about 20,745 (266)

Age-Related Alterations in PON1

2007
Aging is associated with an increased incidence of atherosclerosis. Atherosclerosis is an inflammatory disease initiated by oxidized low density lipoprotein (oxLDL). High density lipoprotein (HDL) is a powerful antioxidant protecting LDL and itself from oxidation as well by detoxifying the hydroperoxides from oxLDL.
I. Seres, T. Fulop, G. Paragh, A. Khalil
openaire   +1 more source

???????????????????? ???????????????? ?? ?????????? ?????????????????? ????????: ???????????????? ???????????????????????????? ?????????????????????????? ???? ???????????? PON1 ???? FTO

2013
Shown no statistically significant differences of functional polymorphisms of genes PON1 and FTO in the determination of the risk of obesity in school-age children. The presence of abnormally burdened alleles does not significantly affect the distribution of body fat mass for healthy children, but there is direct strong correlation between neck ...
openaire   +1 more source

Paraoxonase (PON1) and Organophosphate Toxicity

2007
Paraoxonase (PON1) is a high density lipoprotein-associated enzyme capable of hydrolyzing multiple substrates, including several organophosphorus (OP) insecticides and nerve agents, oxidized lipids and a number of drugs or pro-drugs. Several polymorphisms in the PON1 gene have been described, which have been shown to affect either the catalytic ...
L.G. Costa, T.B. Cole, K.L. Jansen, C.E. Furlong   +3 more
openaire   +1 more source

Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life

World Journal of Biological Psychiatry, 2019
E. Moreira, D. Correia, K. Bonifácio, Juliana Brum Moraes, Fernanda Liboni Cavicchioli, Caroline Sampaio Nunes, S. Nunes, H. Vargas, D. Barbosa, M. Maes   +9 more
semanticscholar   +1 more source

Polymorphisms of MTHFR, eNOS, ACE, AGT, ApoE, PON1, PDE4D, and Ischemic Stroke: Meta-Analysis.

Journal of Stroke & Cerebrovascular Diseases, 2017
L. Wei, Anthony Au, S. Menon, L. Griffiths, Cheah Wee Kooi, Looi Irene, Jiangyang Zhao, Chaeyoung Lee, Avdonina Maria Alekseevna, M. Hassan, Z. A. Aziz   +10 more
semanticscholar   +1 more source

PON1 Structure

2002
Denis Josse, Patrick Masson, Cynthia Bartels, Oksana Lockridge   +3 more
openaire   +1 more source

PON1 Polymorphisms

2002
Victoria H. Brophy, Gail P. Jarvik, Clement E. Furlong   +2 more
openaire   +1 more source

Paraoxonase (PON1) Enzyme and Polymorphisms

2014
Paraoxonase enzyme has initially been identified as a protective barrier against organophosphorus poisoning. In the recent years, a wide range of investigations were conducted on this enzyme and the knowledge about its functions and the etiopathogenetic role in some diseases has been clarified in depth.
KOÇ, Hatice Bige, KAÇAR, Yasemin
openaire   +1 more source

Downregulation of human paraoxonase 1 (PON1) by organophosphate pesticides in HepG2 cells

Environmental Toxicology, 2017
I. Medina-Díaz, N. Ponce-Ruíz, Bryana Ramírez-Chávez, A. Rojas-García, B. Barrón-Vivanco, G. Elizondo, Y. Y. Bernal-Hernández   +6 more
semanticscholar   +1 more source

Serum Levels of Anti-PON1 and Anti-HDL Antibodies as Potential Biomarkers of Premature Atherosclerosis in Systemic Lupus Erythematosus

Thrombosis and Haemostasis, 2017
P. López, J. Rodríguez-Carrio, A. Martínez-Zapico, Á. Pérez-Álvarez, R. López-Mejías, L. Benavente, L. Mozo, L. Caminal-Montero, M. González-Gay, A. Suárez   +9 more
semanticscholar   +1 more source