Results 51 to 60 of about 9,907 (172)
, 2012 The cardio protective functions of HDL are attributed to the HDL-associated proteins like Paraoxonase 1 (PON1). PON1 is associated with HDL through a N-terminal signal peptide. HDL-associated PON1 alone is cardio protective.
D’Souza, C. J. M. +7 more
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Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity
, 2003 Paraoxonase (PON1) is an A-esterase capable of hydrolysing the active metabolites (oxons) of a number of organophosphorus (OP) insecticides such as parathion, diazinon and chlorpyrifos.
Li, Wan-Fen +5 more
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PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos [PDF]
, 2012 Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure ...
Ellison, Corie A +6 more
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Oxidative stress & antioxidants and PON1 in health and disease
, 2008 2nd International Conference on Paraoxonases -- SEP, 2006 -- Hajduszoboszlo, HUNGARYImpairment in oxidative stress/antioxidant balance is an important trigger for a variety of diseases.
Sozmen, Eser Yildirim +3 more
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Investigation of serum paraoxonase 1 (PON1) activity in postprandial lipemia
, 2019 Amaç: Paraoksonaz-1 (PON1) HDL yapısında bulunan, HDL ve LDL’yi oksidasyondan koruyarak aterosklerotik lezyonlardaki oksidatif stresi azaltan antioksidan bir enzimdir.
Altınkaynak, Yahya +5 more
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The growing importance of PON1 in cardiovascular health: a review
, 2012 The wide acceptance of the oxidation theory of atherogenesis has prompted attention to antioxidant mechanisms, particularly the prevention of lipid oxidation by high-density lipoprotein-associated proteins like paraoxonase 1 (PON1) enzyme.
Blackhurst, Diane M. +4 more
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, 2020 The levels and activity of the enzyme paraoxonase 1 affect the vulnerability to the teratogenic effects of organophosphate pesticides. Mutant mice lacking the gene for paraoxonase1 (PON1-/-) are more susceptible to the toxic effects of chlorpyrifos, and ...
Eynav Raykin +4 more
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Human serum paraoxonase (PON1) activity in acute organophosphorous insecticide poisoning
, 2003 40th Annual Meeting of the International-Association-of-Forensic-Toxicologists -- AUG 26-30, 2002 -- PARIS, FRANCEHuman serum paraoxonase (PON1) and perhaps other mammalian paraoxonases catalyzes the hydrolysis of certain organophosphorus (OP ...
Solak, I +4 more
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Distribution of PON1 enzyme activities measured in FF and serum, stratified by PON1 Q192R phenotype.
, 2017 Geometric means and standard deviations (SD) of arylesterase activity (shaded bars) and paraoxonase activity (open bars) presented; differences for enzyme activities in FF and serum are significant (P PON1 Q192R phenotype; * P PON1 Q192R phenotypes; † n =
Michael S. Bloom (406460) +3 more
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Main Determinants of PON1 Activity in Hemodialysis Patients
, 2012 Cardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 ...
Costa, Elísio +13 more
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