Results 71 to 80 of about 6,713 (180)

Evaluation of Paraoxonase1 Polymorphisms in Hypothyroid Patients and Their Relationship with Paraoxonase Activity and Serum Lipids

open access: yesEndocrinology Research and Practice, 2019
Objective: The risk for atherosclerosis increases in hypothyroidism, although its associated mode of pathogenesis has not been determined yet. Paraoxonase1 (PON1) is an enzyme that is antioxidative and antiatherogenic. This study was planned to determine
Ayşen CANİKLİOĞLU   +7 more
doaj   +1 more source

Royal jelly maintains telomere length and antioxidant parameters in the pancreas of streptozotocin-induced rats

open access: yesTrakya University Journal of Natural Sciences
Background: Streptozotocin (STZ) is an agent with selective toxicity targeting pancreatic β-cells and is commonly used to establish models of pancreatic damage.
Selcen Çakır
doaj   +1 more source

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu   +4 more
doaj  

The importance of paraoxonase 1 activity in chronic kidney disease

open access: yesRenal Failure
Paraoxonase 1 (PON1) is one of the most significant antioxidative enzymes associated with high-density lipoprotein (HDL). It has been proved that is involved in the pathogenesis of many diseases including chronic kidney disease (CKD).
Elisabeth C. Samouilidou   +4 more
doaj   +1 more source

Effect of anaerobic training on serum paraoxonase 1 (PON1) activity and role of PON1-L55M  polymorphism

open access: yesKinesiologia Slovenica: scientific journal on sport
Paraoxonase (PON) enzyme family (paraoxonase 1, 2 and 3) has antiatherosclerotic properties. The decreased PON1 enzyme activity (EA), PON1 level and PON1-L55M polymorphism (PON1P) are risk factors for atherosclerosis. Effects of anaerobic training on PON1 levels and the role of PON1P are unclear.
Sevilmis, Ezgi   +6 more
openaire   +2 more sources

Paraoxonase (PON1) and polymorphisms of PON1 gene

open access: yesThe Journal of Japan Atherosclerosis Society, 2000
Tadashi SUEIRO   +4 more
openaire   +2 more sources

Decreased PON1 activity as a biological marker for depressive disorders: a narrative review

open access: yesJournal of Affective Disorders Reports
Background: This study conducts a narrative review to summarize evidence regarding changes in serum/plasma paraoxonase 1 (PON1) activity in patients with major depressive disorder (MDD) or other depressive disorders and assess their possible marker value.
Oleg A. Levada, Oleksandra S. Troian
doaj   +1 more source

Redox-senescence function of PON1 in hepatocellular carcinoma and its non-invasive assessment using super-resolution radiomics: a multi-center study

open access: yesJournal of Translational Medicine
Background Risk stratification in hepatocellular carcinoma (HCC) is limited by the lack of robust biomarkers reflecting tumor biology. The antioxidant enzyme Paraoxonase-1 (PON1) shows prognostic potential, yet its role in tumor tissues and the ...
Chiyu Cai   +12 more
doaj   +1 more source

Somatic Gene Therapy in the Prevention of Toxic Effects of Organophosphate Agents

open access: yesВестник войск РХБ защиты
Medical intervention in poisoning by organophosphate toxic agents (OPA) using atropine sulfate, 2-pyridinaldoxymethyl chloride (2-PAM), diazepam and other similar drugs can prevent the fatal outcome of poisoning.
J. Lakota
doaj   +1 more source

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