Results 141 to 150 of about 45,385 (279)
Advanced Materials, EarlyView.This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang +10 more
wiley +1 more source
Enhancement of solubility of poorly soluble drugs by solid dispersion: An Overview
, 2017 Most of the newly invented chemical drug moieties are poorly water soluble. According to BCS classification, class II and IV drugs are considered as poorly water soluble. So enhancement of oral absorption and bioavailability of solid dosage forms remains
Thyagaraju, K. +5 more
core +2 more sources
Minimally Invasive Delivery of Optical Nanosensors Using Injectable Hydrogels
Advanced Materials Interfaces, EarlyView.Injectable peptide hydrogels offer a minimally invasive delivery platform for single‐walled carbon nanotube (SWCNT)‐based near‐infrared fluorescent sensors, enabling real‐time measurement of drug concentrations. Encapsulated SWCNTs show a dose‐dependent fluorescence response across physiologically relevant concentrations and retain their fluorescence ...
Shirel Kleiner, Gili Bisker
wiley +1 more source
Enhancement of gastrointestinal absorption of poorly water soluble drugs via lipid based systems
, 2004 1056-1065Development of knowledge on lipids has attracted the scientific community for the effective utilization of the natural and synthetic lipids.
Ghosal, Saroj K, Subramanian, Natesan
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PharmaceuticsThe transdermal delivery of non-steroidal anti-inflammatory drugs (NSAIDs) has the potential to overcome some of the major disadvantages relating to oral NSAID usage, such as gastrointestinal adverse events and compliance. However, the poor solubility of
Alexandra Balmanno +3 more
doaj +1 more source
Advanced Materials Interfaces, EarlyView.PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi +9 more
wiley +1 more source
Apparent dissolution rate enhancement of poorly-water soluble drugs by adsorption technique
, 2015 Nearly 70% of the new chemical entities (NCE’s) discovered are poorly-water soluble drugs and the number of poorly-water soluble drugs are increasing rapidly in the drug discovery. Most of the NCE’s are lipophilic and have dissolution rate issues.
Vutukuru, Naresh Kumar Reddy
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Advances in Halide Perovskites for Photon Radiation Detectors
Advanced Materials Technologies, EarlyView.This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang +3 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.A fully organic UV threshold dosimeter is developed by exploiting the oxygen‐sensitive room‐temperature phosphorescence of a purely organic emitter in a polymer matrix. Upon reaching a specific cumulative UV dose, photochemical oxygen depletion triggers a sharp, high‐contrast emission.
Tim Achenbach +3 more
wiley +1 more source
Hydrotropic solubilization of poorly soluble drugs
, 2009 The purpose of the present study is to develop a good solubilization vehicle for various poorly soluble drugs via hydrotropic solubilization. To achieve this goal, we discovered a new hydrotrope, DMBA and it showed more than 1000-fold solubility ...
Kim, Ji Young
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