Results 61 to 70 of about 45,385 (279)

Using fluid bed granulation to improve the dissolution of poorly water-soluble drugs

Brazilian Archives of Biology and Technology, 2012
In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and croscarmellose sodium and then ...
Andrea Ikeda Takahashi, Felipe Rebello Lourenço, Marcelo Dutra Duque, Vladi Olga Consiglieri, Humberto Gomes Ferraz   +4 more
doaj   +1 more source

Using dicationic ionic liquids to upgrade the cytotoxicity and solubility of poorly water-soluble drugs

Journal of Ionic Liquids, 2023
New dicationic ionic liquids (DcILs) based on carboxylic acid-derived, N-acetyl amino acid-derived or bromide anions, and ammonium cations were synthesized and characterized.
Ana B.P. Silva, Ana R. Jesus, Daniela A.S. Agostinho, José M.S.S. Esperança, Alexandre Paiva, Ana R.C. Duarte, Patrícia M. Reis   +6 more
doaj   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

VARIOUS TECHNIQUES ENHANCING BIOAVAILABILTY OF POORLY WATER SOLUBLE DRUGS

, 2013
A drug administered in solution form immediately available for absorption and efficiently absorbed than the same amount of drug administered in a tablet or capsule form.
Nirmala, Nirmala, Thakur, Anil Kumar, Harikumar, S L   +2 more
core   +1 more source

Antisolvent Crystallization of Poorly Water Soluble Drugs

International Journal of Chemical Engineering and Applications, 2013
The enhancement in bioavailability of the drugs is one of the most important concerning aspects of the pharmaceutical industries. Preparation of nanoparticles or microparticles of these drugs is the newest formulation strategies. The size and morphology of a drug are affecting several essential pharmaceutical properties.
Abhijit A. Lonare, Sanjaykumar R. Patel
openaire   +1 more source

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

Advanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell, Emily L. Gulliver, Livia Salvati Manni, Frithjof Herb, Caitlin Welsh, Samuel C. Forster, Andrew J. Clulow, Wye‐Khay Fong   +7 more
wiley   +1 more source

Crosslinked hydrogels—a promising class of insoluble solid molecular dispersion carriers for enhancing the delivery of poorly soluble drugs

Acta Pharmaceutica Sinica B, 2014
Water-insoluble materials containing amorphous solid dispersions (ASD) are an emerging category of drug carriers which can effectively improve dissolution kinetics and kinetic solubility of poorly soluble drugs.
Dajun D. Sun, Ping I. Lee
doaj   +1 more source

Receptor‐Free Identification of Toxic Gases Enabled by Hygroscopic Aqueous Salt Films

Advanced Functional Materials, EarlyView.
Water as a gas sensor coating sounds impossible—until it stops evaporating. Here, hygroscopic salt solutions (LiCl, LiBr, H3PO4) form non‐drying aqueous films on CNT chemiresistors under ambient air. Gases partition into these liquid layers, sometimes transforming into water, and generate salt‐specific resistance fingerprints across a four‐channel ...
Seongwoo Lee, Yun‐Tae Kim, Hwarang Choi, Sanghwan Park, Seongyeop Lim, Chang Young Lee   +5 more
wiley   +1 more source

Datasets for "Dual stimuli-responsive hydrogel for improved colon-targeted delivery of poorly water-soluble drugs"

, 2020
Supporting data for the publication "Dual stimuli-responsive hydrogel for improved colon-targeted delivery of poorly water-soluble ...
Wylie, Matthew; id_orcid, Bayan, Mohammad, Material and Advanced Technologies for Healthcare, McCoy, Colin; id_orcid, School of Pharmacy, Irwin, Nicola, Pharmaceutical Science and Practice   +6 more
core   +1 more source

Production of nanostructured molecular liquids by supercritical CO2 processing

OpenNano, 2017
Stable molecular clusters of ibuprofen and naproxen were prepared in dry ice, by supersonic jet expansion of their supercritical CO2 drug formulations into a liquid nitrogen cooled collection vessel, with up to 80% yield.
Sudhir Kumar Sharma, Abiy D. Woldetsadik, Thomas Blanton, Matthew J. O'Connor, Mazin Magzoub, Ramesh Jagannathan   +5 more
doaj   +1 more source