Results 31 to 40 of about 8,031,804 (248)
Molecular Ecology, 2021 Horizontal gene transfer from viruses to eukaryotic cells is a pervasive phenomenon. Somatic viral integrations are linked to persistent viral infection whereas integrations into germline cells are maintained in host genomes by vertical transmission and ...
C. Crava +14 more
semanticscholar +1 more source
The population genomics of adaptive loss of function
Heredity, 2021 Discoveries of adaptive gene knockouts and widespread losses of complete genes have in recent years led to a major rethink of the early view that loss-of-function alleles are almost always deleterious.
J. G. Monroe +3 more
semanticscholar +1 more source
Stacks 2: Analytical Methods for Paired-end Sequencing Improve RADseq-based Population Genomics
bioRxiv, 2019 For half a century population genetics studies have put type II restriction endonucleases to work. Now, coupled with massively-parallel, short-read sequencing, the family of RAD protocols that wields these enzymes has generated vast genetic knowledge ...
Nicolas C. Rochette +2 more
semanticscholar +1 more source
Advances and opportunities in malaria population genomics
Nature reviews genetics, 2021 Almost 20 years have passed since the first reference genome assemblies were published for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the most important mosquito vector of malaria in sub-Saharan Africa.
D. Neafsey, A. Taylor, B. MacInnis
semanticscholar +1 more source
Implementation Science, 2022 Background Opioids can be effective analgesics, but long-term use may be associated with harms. In 2013, the first national, comprehensive, evidence-based pain management guideline was published, from the Scottish Intercollegiate Guideline Network (SIGN ...
Harry L. Hébert +4 more
doaj +1 more source
BJGP Open, 2021 Background: Care home residents often have multiple cognitive and physical impairments, and are at high risk of adverse drug events (ADEs). Aim: To describe excessive polypharmacy and potentially inappropriate prescribing predisposing care home residents
Clare MacRae +7 more
doaj +1 more source
Explaining microbial population genomics through phage predation [PDF]
, 2009 The remarkable diversity of genes within the pool of prokaryotic genomes belonging to the same species or pan-genome is difficult to reconcile with the widely accepted paradigm which asserts that periodic selection within bacterial populations would ...
Alex Mira +6 more
core +2 more sources
Advances in Whole Genome Sequencing: Methods, Tools, and Applications in Population Genomics. [PDF]
Int J Mol SciWith the rapid advancement of high-throughput sequencing technologies, whole genome sequencing (WGS) has emerged as a crucial tool for studying genetic variation and population structure.
Lu Y +9 more
europepmc +2 more sources
Population genomics analysis with RAD, reprised: Stacks 2
bioRxiv, 2021 Restriction enzymes have been one of the primary tools in the population genetics toolkit for fifty years, being coupled with each new generation of technology to provide a more detailed view into the genetics of natural populations.
A. Rivera-Colón, J. Catchen
semanticscholar +1 more source
Identification of genes related to intramuscular fat content of pigs using genome-wide association study [PDF]
Asian-Australasian Journal of Animal Sciences, 2018 Objective The aim of this study is to identify single nucleotide polymorphisms (SNPs) and genes related to pig IMF and estimate the heritability of intramuscular fat content (IMF). Methods Genome-wide association study (GWAS) on 704 inbred Berkshires was
Sohyoung Won +3 more
doaj +1 more source