Results 41 to 50 of about 8,031,804 (248)

Population genomics and antimicrobial resistance dynamics of Escherichia coli in wastewater and river environments

Communications Biology, 2021
Aquatic environments are key niches for the emergence, evolution and dissemination of antimicrobial resistance. However, the population diversity and the genetic elements that drive the dynamics of resistant bacteria in different aquatic environments are
J. Delgado-Blas, C. M. Ovejero, S. David, N. Montero, William Calero-Cáceres, M. P. Garcillán-Barcia, F. de la Cruz, M. Muniesa, D. Aanensen, B. González-Zorn   +9 more
semanticscholar   +1 more source

Population genomics of domestic and wild yeasts [PDF]

, 2008
The natural genetics of an organism is determined by the distribution of sequences of its genome. Here we present one- to four-fold, with some deeper, coverage of the genome sequences of over seventy isolates of the domesticated baker's yeast ...
A Demogines, A Goffeau, Alan M. Moses, Alex N. Nguyen, Alexander van Oudenaarden, Anders Blomberg, Austin Burt, Casey M. Bergman, David B. H. Barton, David M. Carter, DM Carter, DM Ruderfer, Douda Bensasson, E Aa, E Mancera, Edward J. Louis, Elizabeth Bailes, F Tajima, F Wiens, Frances Smith, G Liti, G Liti, GI Naumov, Gianni Liti, HA Kuehne, HW Mewes, Ian Goodhead, Ian N. Roberts, IJ Tsai, IS Pretorius, Isheng J. Tsai, J Diamond, J Warringer, JC Fay, JH McDonald, JK Pritchard, JL Legras, Jonas Warringer, JP Sampaio, Leopold Parts, M Bulmer, M Kellis, Matthew Jones, Michael A. Quail, Michael J. T. O’Kelly, N Siva, PD Sniegowski, Richard Durbin, RM Clark, Robert P. Davey, Sarah Sims, Stephen A. James, V Koufopanou, Vassiliki Koufopanou, W Wei   +54 more
core   +2 more sources

Key Insights and Research Prospects at the Dawn of the Population Genomics Era for Verticillium dahliae.

Annual Review of Phytopathology, 2021
The genomics era has ushered in exciting possibilities to examine the genetic bases that undergird the characteristic features of Verticillium dahliae and other plant pathogens.
Jieyin Chen, S. Klosterman, Xiaoping Hu, X. Dai, K. Subbarao   +4 more
semanticscholar   +1 more source

Coalescence 2.0: a multiple branching of recent theoretical developments and their applications [PDF]

, 2014
Population genetics theory has laid the foundations for genomics analyses including the recent burst in genome scans for selection and statistical inference of past demographic events in many prokaryote, animal and plant species.
Lemaire, Christophe, Tellier, Aurelien
core   +5 more sources

Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource

bioRxiv, 2021
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome datasets from natural populations of this species have been published over the last 20 years.
M. Kapun, J. C. Nunez, María Bogaerts-Márquez, Jesús Murga-Moreno, M. Paris, J. Outten, Marta Coronado-Zamora, Courtney Tern, Omar Rota-Stabelli, M. G. García Guerreiro, Sònia Casillas, D. Orengo, E. Puerma, M. Kankare, L. Ometto, V. Loeschcke, B. S. Onder, J. Abbott, S. Schaeffer, S. Rajpurohit, Emily L. Behrman, M. Schou, T. Merritt, B. Lazzaro, Amanda Glaser-Schmitt, E. Argyridou, Fabian Staubach, Yun Wang, E. Tauber, S. Serga, D. Fabian, K. Dyer, C. Wheat, J. Parsch, Sonja Grath, M. Veselinovic, M. Stamenković-Radak, Mihailo Jelić, Antonio J. Buendía-Ruíz, M. J. Gómez-Julián, M. Espinosa‐Jiménez, Francisco D. Gallardo-Jiménez, Aleksandra Patenković, K. Erić, M. Tanasković, Anna Ullastres, L. Guio, Miriam Merenciano, S. Guirao-Rico, V. Horváth, Darren J Obbard, E. Pasyukova, V. Alatortsev, C. Vieira, J. Vieira, J. R. Torres, I. Kozeretska, Oleksandr M. Maistrenko, C. Montchamp-Moreau, D. Mukha, Heather E. Machado, A. Barbadilla, D. Petrov, P. Schmidt, Josefa González, T. Flatt, A. Bergland   +66 more
semanticscholar   +1 more source

A tug-of-war between driver and passenger mutations in cancer and other adaptive processes [PDF]

, 2014
Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few key mutations that drive rapid population growth and carcinogenesis ...
Korolev, Kirill S., McFarland, Christopher, Mirny, Leonid   +2 more
core   +2 more sources

Population genomics of parallel adaptation [PDF]

Molecular Ecology, 2020
Parallel evolution is one of the striking patterns in nature. The presence of repeated evolution of the same phenotypes, suites of traits, and adaptations suggests a strong role for natural selection in shaping biological diversity. The reasoning is straightforward: each instance of repeated evolution makes it less likely that these features evolved ...
Meng Yuan, John R. Stinchcombe
openaire   +2 more sources

Population genomics provides insights into the evolution and adaptation to humans of the waterborne pathogen Mycobacterium kansasii

Nature Communications, 2021
Mycobacterium kansasii can cause serious pulmonary disease. It belongs to a group of closely-related species of non-tuberculous mycobacteria known as the M. kansasii complex (MKC).
Tao Luo, P. Xu, Yangyi Zhang, Jessica L. Porter, M. Ghanem, Qingyun Liu, Yuan Jiang, Jing Li, Qing Miao, Bijie Hu, B. Howden, J. Fyfe, M. Globan, Wencong He, P. He, Yi-ting Wang, Hou-ming Liu, H. Takiff, Yanlin Zhao, Xinchun Chen, Q. Pan, M. Behr, T. Stinear, Q. Gao   +23 more
semanticscholar   +1 more source

Population genomics of ancient and modern Trichuris trichiura

Nature Communications, 2021
The neglected tropical disease trichuriasis is caused by the whipworm Trichuris trichiura, a soil-transmitted helminth that has infected humans for millennia. Today, T.
S. Doyle, M. J. Søe, P. Nejsum, M. Betson, P. Cooper, Lifei Peng, Xing-Quan Zhu, Ana L. Sanchez, Gabriela Matamoros, Gustavo A. Sandoval, C. Cutillas, L. A. Tchuenté, Z. Mekonnen, S. Ame, Harriet Namwanje, B. Levecke, M. Berriman, B. Fredensborg, C. Kapel   +18 more
semanticscholar   +1 more source

A publication-wide association study (PWAS), historical language models to prioritise novel therapeutic drug targets

Scientific Reports, 2023
Most biomedical knowledge is published as text, making it challenging to analyse using traditional statistical methods. In contrast, machine-interpretable data primarily comes from structured property databases, which represent only a fraction of the ...
David Narganes-Carlón, Daniel J. Crowther, Ewan R. Pearson   +2 more
doaj   +1 more source