Results 101 to 110 of about 3,139,827 (291)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Advancing Semiochemical Tools for Mountain Pine Beetle Management: Dendroctonus ponderosae Responses to Saprophytic Fungal Volatiles

Metabolites
Background/Objectives: Within their host trees, mountain pine beetles (MPBs, Dendroctonus ponderosae) interact with many fungal species, each releasing a unique profile of volatile organic compounds (VOCs). The FVOCs released by the two primary symbionts
Leah Crandall, Rashaduz Zaman, Guncha Ishangulyyeva, Nadir Erbilgin   +3 more
doaj   +1 more source

Gender wage differentials in Brazil : trends over a turbulent era [PDF]

Since the late 1980s, macroeconomic and trade reform in Brazil appears to have been accompanied by a substantial improvement in the position of women compared with men in the labor market, despite only modest changes to labor market institutions.
Andrew Henley, Francisco Galrao Carneiro, G. Reza Arabsheibani   +2 more
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Camera Traps: A Novel Method to Estimate Numbers of Nesting Sea Turtles

Ecology and Evolution
Abundance estimates are difficult to obtain for many animal groups, yet essential for endangered species management and conservation. For sea turtles, estimates are made from ground counts of nesting females, tracks, and nests, but these are challenging ...
Holly J. Stokes, Graeme C. Hays, Kimberley L. Stokes, Nicole Esteban   +3 more
doaj   +1 more source

Monitoring the Dutch Phytophtora infestans population for virulence against new R-genes [PDF]

New possibilities offered by marker assisted breeding and GMO breeding have sparked renewed international efforts to breed for durable potato late blight resistance.
Bekkum, P.J., van, Bosch, G.B.M., van den, Evenhuis, A., Förch, M.G., Vossen, J.H.   +4 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Assessing Applicability of eDNA‐Based Sampling for Population Monitoring of Leatherback Turtles in the Northeast Indian Ocean

Environmental DNA
Current population genetics studies of sea turtles primarily rely on invasive tissue sampling or blood draws, which involve the capture and handling of the animals that require specific permits and resources.
Maslim As‐singkily, Reindert Nijland, Iliana Bista, Peter H. Dutton, Leontine E. Becking   +4 more
doaj   +1 more source

Surveying populations of breeding grebes in prairie parkland Canada: Estimation problems and conservation applications

Wildlife Society Bulletin, 2014
Annual ground surveys of mid‐continent waterfowl may provide a monitoring framework for other wetland‐associated species. We used a repeated‐counts method to estimate detection probabilities (ρˆ) of adult horned (Podiceps auritus) and pied‐billed ...
Daniel D. Routhier, Kevin W. Dufour, Mark T. Bidwell, Robert G. Clark   +3 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source