Results 91 to 100 of about 39,580 (190)

Unlocking the secret life of blue mussels: Exploring connectivity in the Skagerrak through biophysical modeling and population genomics

Evolutionary Applications
Knowledge of functional dispersal barriers in the marine environment can be used to inform a wide variety of management actions, such as marine spatial planning, restoration efforts, fisheries regulations, and invasive species management.
Malin Gustafsson, Åsa Strand, Ane T. Laugen, Jon Albretsen, Carl André, Göran Broström, Per Erik Jorde, Halvor Knutsen, Olga Ortega‐Martinez, Marte Sodeland, Malin Waern, Anna‐Lisa Wrange, Pierre De Wit   +12 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Population Structure of Morpho helenor peleides (Kollar, 1850) (Lepidoptera: Nymphalidae) Under Different Land Uses in the Caribbean Region of Colombia

Insects
Morpho butterflies have the potential to act as a bioindicator species, since they are sensitive to changes in land uses and forest degradation; there have been few population studies of butterflies in the Caribbean region of Colombia.
Carlos Elías Altamar-Bolívar, Juan David González-Trujillo, Luis G. Quijano-Cuervo, María Inés Moreno-Pallares, Neis José Martínez-Hernández   +4 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Hardy–Weinberg Equilibrium Filtering in Population Genomics: Empirical Review and Decision Framework for Improved Practice

Ecology and Evolution
Hardy–Weinberg equilibrium (HWE) filtering remains widely used in population genomics, but its application remains inconsistent, often lacking detailed justification, and not always aligned with biological context.
Yu‐Hsun Hsu
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Population recovery and demographically constrained growth of Bezoar goat (Capra aegagrus) and Asian mouflon (Ovis gmelinii) in the Leopard Range of Nakhchivan, Azerbaijan

Acta Biologica Sibirica
The population status of the bezoar goat (Capra aegagrus) and the Asian mouflon (Ovis gmelinii), the primary prey of the Persian leopard (Panthera pardus), was assessed within the leopard's range in the southeastern part of the Nakhchivan Autonomous ...
Elmar Babaev, Ismail Mammadov, Parviz Fatullayev, Elshad Askerov, Konul Akhmedova, Dashgin Ganbarov, Samir Gyliyev   +6 more
doaj   +1 more source

Genealogical structuring of a population.

Collegium antropologicum, 2001
The study observed population of 484 generation restrictive genealogies collected in four Croatian regions during 1970/71 within "The study of fat and carbohydrate metabolism indicators correlated with the occurrence of diabetes in animal fat and oil consuming population groups".
Kujundžić Tiljak, M., Kern, J., Ivanković, D., Tiljak, H., Vuletić, S.   +4 more
openaire   +4 more sources