Results 101 to 110 of about 148,131 (169)

Metagenomics to Identify Viral Communities Associated with Porcine Respiratory Disease Complex in Tibetan Pigs in the Tibetan Plateau, China

Pathogens
Tibetan pig is a unique pig breed native to the Qinghai–Tibet Plateau. To investigate viral communities associated with porcine respiratory disease complex (PRDC), 167 respiratory samples were collected from Tibetan pigs in the Ganzi Tibetan autonomous ...
Long Zhou, Han Zhou, Yandi Fan, Jinghao Wang, Rui Zhang, Zijing Guo, Yanmin Li, Runmin Kang, Zhidong Zhang, Danjiao Yang, Jie Liu   +10 more
doaj   +1 more source

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]

, 2012
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
Ebermann, L., Čičin-Šain, Luka, Luka Čičin-Šain, Rosaely Casalegno-Garduño (111456), Carlos A Guzmán, Ruzsics, Zsolt, van Rooijen, Nico, Koszinowski, U., van Rooijen, N., Ulrich Koszinowski, Linda Ebermann (111451), Zsolt Ruzsics (75383), Ruzsics, Z., Nico van Rooijen, Guzman, C.A., Casalegno-Garduno, R., Ulrich Koszinowski (111457), Ruzsics Zsolt, Casalegno-Garduño, Rosaely, Nico van Rooijen (4110211), Koszinowski, Ulrich H., Zsolt Ruzsics, Carlos A. Guzmán (111454), Luka Čičin-Šain (111459), Guzmán, Carlos A., Rooijen, N. van, Guzmán Carlos A., Ebermann Linda, Linda Ebermann, Cicin-Sain, L., Čičin-Šain Luka, Guzmán, Carlos A, Casalegno-Garduño Rosaely, Koszinowski, Ulrich, Rosaely Casalegno-Garduño, Ebermann, Linda, van Rooijen Nico, Koszinowski Ulrich   +37 more
core   +2 more sources

Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3. [PDF]

, 1992
We have previously defined ie3 as a coding region located downstream of the ie1 gene which gives rise to a 2.75-kb immediate-early (IE) transcript. Here we describe the structural organization of the ie3 gene, the amino acid sequence of the gene product,
Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Keil, Günther M.   +3 more
core   +1 more source

Genomic evidence of the blood virome and bacteriome provides insights into prevalence, evolution, and susceptibility-related genes across Eurasian pigs

BMC Genomics
Background Infectious diseases are among the primary constraints to pig production, and the globalization of the pig industry has contributed to the emergence and spread of pathogens.
Zhen Liu, Shi-Yu Lu, Si-Jia Ma, Lei Zhou, Wan-Ying Li, Heng Du, Jian-Feng Liu   +6 more
doaj   +1 more source

First Report of Triple Viral Co-Infection (PPV, PCV2, PCMV) in Wild Boars in the Western Balkans

Pathogens
Wild boars are recognized reservoirs of numerous viral pathogens, posing a significant risk to domestic pig populations, particularly in areas with poor biosecurity.
Dimitrije Glišić, Sofija Šolaja, Kukilo Stevan, Vesna Milićević, Miloš Vučićević, Jelena Aleksić, Dajana Davitkov   +6 more
doaj   +1 more source

Integrative analysis of swine infectious diseases in the context of xenotransplantation

International Journal of Infectious Diseases
Background: The initiation of clinical pig xenotransplantation trials offers the prospect of alleviating global organ shortage. However, current knowledge of swine-derived microorganisms relevant to xenotransplantation remains fragmented due to the ...
Jiayu Li, Kai Liu, Muhammad Ameen Jamal, Kaixiang Xu, Wenmin Cheng, Baoyu Jia, Hong-Ye Zhao, Hongzhou Lu, Jay A. Fishman, Hong-Jiang Wei   +9 more
doaj   +1 more source

Restoration of cytomegalovirus antigen presentation by gamma interferon combats viral escape. [PDF]

, 1994
An immediate-early protein of murine cytomegalovirus (MCMV), pp89, elicits an immunodominant and protective major histocompatibility complex (MHC) class I Ld-restricted CD8+ T-lymphocyte response.
Ruppert, Siegfried, Koszinowski, Ulrich H., Lucin, Pero, Jonjic, Stipan, Hengel, Hartmut   +4 more
core   +1 more source

Human cytomegalovirus (HCMV) replication dynamics in HCMV-naive and -experienced immunocompromised hosts [PDF]

, 2002
Human cytomegalovirus (HCMV) can infect both HCMV-naive and -experienced transplant patients. In this study, the growth rate of HCMV in HCMV-naive hosts (1.82 units/day; 95% confidence interval [CI], 1.44-2.56 units/day) was shown to be significantly ...
Emery, VC, Griffiths, PD, Hassan-Walker, AF, Burroughs, AK   +3 more
core  

The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights

Biomedicines
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation.
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Maria Leuschen, Felicia Wall, Julia Radan, Elisabeth Neumann, Maren Mokelke, Ines Buttgereit, Sebastian Michel, Reinhard Ellgass, Katja Gieseke, Stig Steen, Audrius Paskevicius, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Martin B. Müller, Matthias Längin   +23 more
doaj   +1 more source

Identification and expression of a murine cytomegalovirus early gene coding for an Fc receptor [PDF]

, 1994
Several herpesviruses, including cytomegalovirus, induce receptors for the Fc domain of murine immunoglobulin G (IgG) molecules. Viral genes coding for these receptors have been characterized only for alphaherpesviruses. In this report, we describe a new
Eggers, Maren, Thäle, Regine, Koszinowski, Ulrich H., Lucin, Pero, Schneider, Karin   +4 more
core