Results 91 to 100 of about 521,449 (181)

A Structural Characterization of the Core Post-fusion Porcine Endogenous Retrovirus Fusion Protein [PDF]

, 2022
Porcine endogenous retroviruses (PERVs) are an understudied endogenous retrovirus that can infect human cells. PERV envelope glycoproteins have also been proposed as swine syncytin candidates.
Dean, Trevor Thomas
core   +1 more source

The potential advantages of transplanting organs from pig to man: A transplant Surgeon′s view

Indian Journal of Urology, 2007
Once pig organs can be transplanted into humans, transplantation will move into a new era. There will be unlimited access to undamaged organs and cells for transplantation and, eventually, donation from deceased or live human beings will become obsolete.
Carl G Groth
doaj   +1 more source

Identification of a novel type C porcine endogenous retrovirus: evidence that copy number of endogenous retroviruses increases during host inbreeding

, 2001
Different classes of porcine endogenous retroviruses (PERVs), which have the potential to infect humans during xenotransplantation, have been isolated from the pig genome.
Mang, R., Maas, J., Goudsmit, J., Chen, X., van der Kuyl, A. C.   +4 more
core   +1 more source

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair [PDF]

, 2011
Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that ...
Palmarini, M., Ferri, N., Varasano Vincenzo, Murgia, C., Murgia C., Palmarini M., Vincenzo Varasano, Varasano, V., de las Heras Marcelo, Ceesay O., Marcelo de las Heras, Ferri Nicola, Caporale Marco, Di Francesco Gabriella, de las Heras M., Ceesay, O., Murgia Claudio, Palmarini Massimo, Nicola Ferri, Varasano V., de las Heras, M., Di Francesco G., Ousman Ceesay, Ferri N., Marco Caporale, Massimo Palmarini, Caporale M., Di Francesco, G., Gabriella Di Francesco, Claudio Murgia, Ceesay Ousman, Caporale, M.   +31 more
core   +1 more source

AN69 Hollow Fiber Membrane will Reduce but Not Abolish the Risk of Transmission of Porcine Endogenous Retroviruses

Cell Transplantation, 2005
As the risk of porcine endogenous retrovirus (PERV) infection is a major obstacle to the xenotransplantation of porcine tissue, we investigated whether an AN69 hollow fibre membrane, used for islets of Langerhans transplantation, could prevent the ...
Oleg Pakhomov, Lionel Martignat, Jiri Honiger, Béatrice Clémenceau, Pierre Säi, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

Porcine Endogenous Retrovirus Encodes Xenoantigens Involved in Porcine Cellular Xenograft Rejection by Mice

Transplantation, 2005
Identification of the antigens that stimulate transplant rejection can help develop graft-specific antirejection strategies. The xenoantigens recognized during rejection of porcine cellular xenografts have not been clearly defined, but it has been assumed that major histocompatibility complex (MHC) xenoantigens are involved.The role of porcine ...
Simeonovic, Charmaine, Ziolkowski, Andrew, Popp, Sarah, Milburn, Peter J, Lynch, Celina-Anne, Hamilton, Peter, Harris, Karla, Brown, Debra, Bain, Simon, Wilson, James Dennis, Gibbs, Adrian   +10 more
openaire   +3 more sources

The Use of Pancreas Biopsy Scoring Provides Reliable Porcine Islet Yields While Encapsulation Permits the Determination of Microbiological Safety

Cell Transplantation, 2005
For clinical xenogenic islet transplantation to be successful, several requirements must be met. Among them is a sizeable and reliable source of fully functional and microbiologically safe islets.
Lawrence S. Gazda, Hollie Adkins, Johannah A. Bailie, Wendy Byrd, Lisa Circle, Bryan Conn, Carolyn H. Diehl, Richard D. Hall, Albert L. Rubin, Barry H. Smith   +9 more
doaj   +1 more source

An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs

Вавиловский журнал генетики и селекции, 2017
Pig is the most promising species for transplantation of organs and cells into humans, although implementation of xenotransplantation in clinical practice has been hindered by the risk of infecting the recipient with zoonotic infectious diseases. Porcine
R. B. Aitnazarov, S. V. Nikitin, G. V. Kontsevaya, M. I. Voevoda, N. S. Yudin   +4 more
doaj   +1 more source

An integrase of endogenous retrovirus is involved in maternal mitochondrial DNA inheritance of the mouse. [PDF]

, 2008
The mechanism of maternal mitochondrial DNA (mtDNA) inheritance in animals can be said to be the selective elimination of sperm mtDNA via the elimination factor of the egg and a sperm mitochondria-specific factor. In 2005, we clarified that t-tpis (Spag1
Kohno, Shigeru, Omagari, Katsuhisa, Hayashida, Kenji, Masuda, Jun-Ichi   +3 more
core   +1 more source

Analysis of spread of endogenous retroviruses (PERVs) of subtypes A and C in genomes of pigs of Ukrainian breeds and their correlation with fat deposition in carcasses

Животновъдни науки, 2021
The article presents the results of the analysis of the frequency of PERV retroviruses of subtypes A and C in populations of pigs of Ukrainian and foreign breeds.
Tetiana Mikolaivna Ryk
doaj