Results 81 to 90 of about 7,153 (189)

Porcine Endogenous Retrovirus Encodes Xenoantigens Involved in Porcine Cellular Xenograft Rejection by Mice

Transplantation, 2005
Identification of the antigens that stimulate transplant rejection can help develop graft-specific antirejection strategies. The xenoantigens recognized during rejection of porcine cellular xenografts have not been clearly defined, but it has been assumed that major histocompatibility complex (MHC) xenoantigens are involved.The role of porcine ...
Simeonovic, Charmaine, Ziolkowski, Andrew, Popp, Sarah, Milburn, Peter J, Lynch, Celina-Anne, Hamilton, Peter, Harris, Karla, Brown, Debra, Bain, Simon, Wilson, James Dennis, Gibbs, Adrian   +10 more
openaire   +3 more sources

Identification of stable reference genes for quantitative PCR in koalas [PDF]

, 2018
To better understand host and immune response to diseases, gene expression studies require identification of reference genes with stable expression for accurate normalisation.
A Kappel, A Radonic, B Artegiani, CA Waugh, CL Andersen, D Kim, DG Ginzinger, F Almeida-Oliveira, F Bartz, G Bamias, GS Meers, GS Simmons, IE Maher, IE Maher, J Vandesompele, J Woinarski, J Yperman, JJ Hanger, K Ahn, KC Thomas, KM Morris, M Kubista, M Pertea, MA Valasek, MW Pfaffl, N Silver, OT Ong, P Brym, PD Lee, PJ Canfield, QL Zhang, R Tarlinton, R Tarlinton, RK Das, S Bages, SA Bustin, SA Bustin, T Burmeister, T Nolan, V Gonzalez-Astudillo, Y Zhang   +40 more
core   +4 more sources

Comprehensive Protocols for Detecting Xenotransplantation-Relevant Viruses

Methods and Protocols
Xenotransplantation using pig cells, tissues, or organs is advancing toward clinical application to address the shortage of human donor organs for treating organ failure.
Hina Jhelum, Benedikt B. Kaufer, Joachim Denner   +2 more
doaj   +1 more source

A metagenomic comparison of endemic viruses from broiler chickens with runting stunting syndrome and from normal birds [PDF]

, 2016
Runting-stunting syndrome (RSS) in broiler chickens is an enteric disease that causes significant economic losses to poultry producers worldwide due to elevated feed conversion ratios, decreased body weight during growth, and excessive culling.
Devaney, Ryan, Meharg, Caroline, Smyth, Victoria, Trudgett, Alan, Trudgett, James   +4 more
core   +1 more source

The potential advantages of transplanting organs from pig to man: A transplant Surgeon′s view

Indian Journal of Urology, 2007
Once pig organs can be transplanted into humans, transplantation will move into a new era. There will be unlimited access to undamaged organs and cells for transplantation and, eventually, donation from deceased or live human beings will become obsolete.
Carl G Groth
doaj   +1 more source

AN69 Hollow Fiber Membrane will Reduce but Not Abolish the Risk of Transmission of Porcine Endogenous Retroviruses

Cell Transplantation, 2005
As the risk of porcine endogenous retrovirus (PERV) infection is a major obstacle to the xenotransplantation of porcine tissue, we investigated whether an AN69 hollow fibre membrane, used for islets of Langerhans transplantation, could prevent the ...
Oleg Pakhomov, Lionel Martignat, Jiri Honiger, Béatrice Clémenceau, Pierre Säi, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology [PDF]

, 2017
Human Endogenous Retroviruses (HERVs) are ancient infection relics constituting ~8% of our DNA. While HERVs' genomic characterization is still ongoing, impressive amounts of data have been obtained regarding their general expression across tissues. Among
Grandi, Nicole, Tramontano, Enzo
core   +1 more source

The Use of Pancreas Biopsy Scoring Provides Reliable Porcine Islet Yields While Encapsulation Permits the Determination of Microbiological Safety

Cell Transplantation, 2005
For clinical xenogenic islet transplantation to be successful, several requirements must be met. Among them is a sizeable and reliable source of fully functional and microbiologically safe islets.
Lawrence S. Gazda, Hollie Adkins, Johannah A. Bailie, Wendy Byrd, Lisa Circle, Bryan Conn, Carolyn H. Diehl, Richard D. Hall, Albert L. Rubin, Barry H. Smith   +9 more
doaj   +1 more source

Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species [PDF]

, 2009
In this study, we first demonstrate that endogenous hBST-2 is predominantly expressed on the plasma membrane of a human T cell line, MT-4 cells, and that Vpu-deficient HIV-1 was less efficiently released than wild-type HIV-1 from MT-4 cells. In addition,
Kei Sato, Seiji P Yamamoto, Naoko Misawa, Takeshi Yoshida, Takayuki Miyazawa, Yoshio Koyanagi   +5 more
core   +1 more source

An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs

Вавиловский журнал генетики и селекции, 2017
Pig is the most promising species for transplantation of organs and cells into humans, although implementation of xenotransplantation in clinical practice has been hindered by the risk of infecting the recipient with zoonotic infectious diseases. Porcine
R. B. Aitnazarov, S. V. Nikitin, G. V. Kontsevaya, M. I. Voevoda, N. S. Yudin   +4 more
doaj   +1 more source