Results 131 to 140 of about 882 (164)

Riboflavin transporter: evidence of a role as entry receptor for chimpanzee endogenous retrovirus. [PDF]

Virus Evol
AbuEed L, Miyake A, Wanjala N, Pramono D, Abdillah D, Imamura M, Shimojima M, Denner J, Kawasaki J, Nishigaki K.   +9 more
europepmc   +1 more source

Current status of pancreatic islet xenotransplantation. [PDF]

Clin Transplant Res
Kim JM, Park CG.
europepmc   +1 more source

Contributions of Europeans to Xenotransplantation Research: 2. Pig Islet and Cell Xenotransplantation. [PDF]

Transpl Int
Bottino R, Vasudev K, Iwanczyk Z, Cozzi E, Cooper DKC.   +4 more
europepmc   +1 more source

CRISPR Technology Acts as a Dual-Purpose Tool in Pig Breeding: Enhancing Both Agricultural Productivity and Biomedical Applications. [PDF]

Biomolecules
Fu B, Ma H, Huo X, Zhu Y, Liu D.
europepmc   +1 more source

Application of Methods Detecting Xenotransplantation-Relevant Viruses for Screening German Slaughterhouse Pigs. [PDF]

Viruses
Jhelum H, Kaufer B, Denner J.
europepmc   +1 more source

Porcine endogenous retroviruses (PERVs): adaptation to human cells and attempts to infect small animals and non-human primates.

Annals of transplantation, 2002
J, Denner, V, Specke, J, Schwendemann, S J, Tacke   +3 more
openaire   +1 more source

Pig Xenotransplantation in Beta Cell Replacement: Addressing Challenges and Harnessing Potential for Type 1 Diabetes Therapy. [PDF]

Transpl Int
Piemonti L, Citro A, Tomajer V, Partelli S, Caldara R.   +4 more
europepmc   +1 more source

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The origin of porcine endogenous retroviruses (PERVs)

Archives of Virology, 2021
Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs, and they produce viral particles that are able to infect human cells and therefore pose a special risk for xenotransplantation. In contrast to other pig microorganisms that also pose a risk, such as porcine cytomegalovirus and hepatitis E virus, PERVs cannot be eliminated
Joachim Denner
openaire   +4 more sources

Porcine endogenous retroviruses (PERVs): Generation of specific antibodies, development of an immunoperoxidase
assay (IPA) and inhibition by AZT

Xenotransplantation, 2001
Abstract: Xenotransplantation may be associated with the risk of transmission of microorganisms. In particular, the porcine endogenous retroviruses (PERV) have raised concerns as in vitro experiments show susceptibility of human cells for PERV infection.
O, Stephan, J, Schwendemann, V, Specke, S J, Tacke, K, Boller, J, Denner   +5 more
openaire   +4 more sources

Inhibition of porcine endogenous retroviruses (PERVs) in primary porcine cells by RNA interference using lentiviral vectors

Archives of Virology, 2006
A potential risk in pig-to-human xenotransplantation is the transmission of PERVs to human recipients. Here we show for the first time the inhibition of PERV expression in primary porcine cells by RNA interference using lentiviral vectors. Cells were transduced with lentiviral vectors coding for short hairpin (sh) RNAs directed against PERV.
B, Dieckhoff, A, Karlas, A, Hofmann, W A, Kues, B, Petersen, A, Pfeifer, H, Niemann, R, Kurth, J, Denner   +8 more
openaire   +2 more sources