Results 21 to 30 of about 33,056 (253)
mBio, 2017 Modular bacteriocins represent a major group of secreted protein toxins with a narrow spectrum of activity, involved in interference competition between Gram-negative bacteria.
Maarten G. K. Ghequire +4 more
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Structural Insights into Clostridium perfringens Delta Toxin Pore Formation.
PLoS ONE, 2013 Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Jessica Huyet +5 more
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The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States
Membranes, 2021 The electrochemical gradients established across cell membranes are paramount for the execution of biological functions. Besides ion channels, other transporters, such as exogenous pore-forming toxins, may present ionic selectivity upon reconstitution in
Andrew Bogard +6 more
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Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins
Toxins, 2018 Permeabilization of the plasma membrane represents an important threat for any cell, since it compromises its viability by disrupting cell homeostasis.
Asier Etxaniz +3 more
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Pore Forming Protein Induced Biomembrane Reorganization and Dynamics: A Focused Review
Frontiers in Molecular Biosciences, 2021 Pore forming proteins are a broad class of pathogenic proteins secreted by organisms as virulence factors due to their ability to form pores on the target cell membrane.
Ilanila Ilangumaran Ponmalar +4 more
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Inhibition of Pore-Forming Proteins
Toxins, 2019 Perforation of cellular membranes by pore-forming proteins can affect cell physiology, tissue integrity, or immune response. Since many pore-forming proteins are toxins or highly potent virulence factors, they represent an attractive target for the ...
Neža Omersa +2 more
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DEFENSE AND DEATH RESPONSES TO PORE FORMING TOXINS [PDF]
Biotechnology and Genetic Engineering Reviews, 2009 Pore forming toxins (PFT) are important virulence factors produced by bacteria to kill eukaryotic cells by forming holes in the cellular membrane. They represent a diverse group of proteins with a wide range of target cells. Although the amino acid sequence is not conserved among the different PFT, many of them share some aspects of their mechanism of ...
Angeles, Cancino-Rodezno +3 more
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The Ins and Outs of Anthrax Toxin
Toxins, 2016 Anthrax is a severe, although rather rare, infectious disease that is caused by the Gram-positive, spore-forming bacterium Bacillus anthracis. The infectious form is the spore and the major virulence factors of the bacterium are its poly-γ-D-glutamic ...
Sarah Friebe +2 more
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Recent Insights into Clostridium perfringens Beta-Toxin
Toxins, 2015 Clostridium perfringens beta-toxin is a key mediator of necrotizing enterocolitis and enterotoxemia. It is a pore-forming toxin (PFT) that exerts cytotoxic effect.
Masahiro Nagahama +5 more
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Cellular and Molecular Life Sciences, 2002 Pore-forming toxins are widely distributed proteins which form lesions in biological membranes. In this review, bacterial pore-forming toxins are treated as a paradigm and discussed in terms of the structural principles on which they work. Then, a large family of bacterial toxins, the cholesterol-binding toxins, are analyzed in depth to provide an ...
openaire +3 more sources