Results 11 to 20 of about 180 (136)
Regulation of the expression of ferrochelatase in a murine model of diabetes mellitus type I [PDF]
Biochemistry and Biophysics ReportsBackground: Diabetes produces changes on cellular hemeprotein metabolism. The last enzyme of heme biosynthetic pathway is ferrochelatase (FECH), an enzyme that catalyzes the insertion of ferrous ion into protoporphyrin IX to produce heme. The aim of this
Leda María Oliveri +2 more
doaj +2 more sources
International Journal of Photoenergy, 2014 Photodynamic therapy (PDT) is a treatment modality for tumours and other accessible lesions based on the combination of light and a photosensitizer (PS) accumulated in the target tissue. The main disadvantage of PDT is PS retention after treatment during
Leandro Mamone +5 more
doaj +2 more sources
Porfirias: un grupo de enfermedades subdiagnosticadas y la importancia de un diagnóstico apropiado
Qhalikay Revista De Ciencias De La Salud, 2022 Las porfirias comprenden un grupo de ocho tipos diferentes de desórdenes genéticos en la vía de la síntesis del grupo hemo, con la característica de que sus manifestaciones clínicas pueden confundirse con las de otras patologías médicas.
Jennifer Vizcaino-Carruyo +2 more
exaly +2 more sources
Acute intermittent porphyria: A case report [PDF]
Biomedica, 2020 El término ‘porfiria’ proviene del griego ‘porphyra’ y alude a un grupo heterogéneo de trastornos metabólicos causados por una deficiencia enzimática en la biosíntesis del grupo hemo. La causa de la porfiria intermitente aguda es la deficiencia de la enzima deaminasa del porfobilinógeno.Se presenta el caso de una mujer de 40 años que presentó dolor ...
Bustos J, Vargas L, Quintero R.
europepmc +4 more sources
Trypanocidal activity of thioamide-substituted imidazoquinolinone: electrochemical properties and biological effects. [PDF]
Evid Based Complement Alternat Med, 2013 Three thioamide‐substituted imidazoquinolinone, which possess a heterocyclic center similar to tryptanthrin and are named C1, C2, and C3, were studied regarding (a) their in vitro anti‐Trypanosoma cruzi activity, (b) their cytotoxicity and electrochemical behaviour, and (c) their effect on cell viability, redox state, and mitochondrial function.
Frank FM +5 more
europepmc +2 more sources
Incidencia y prevalencia de la protoporfiria eritropoyética en Colombia, 2014-2018
Actas Dermo-Sifiliográficas, 2021 Resumen En los ultimos anos se han producido importantes avances en la genetica de las porfirias y, concretamente, en las porfirias eritropoyeticas —protoporfiria eritropoyetica (PPE) y porfiria eritropoyetica congenita (PEC)—, que han dado lugar a una nueva concepcion de las mismas como enfermedades no monogenicas.
D.A. Jaramillo-Calle
doaj +2 more sources
Porfiria Aguda como etiología infrecuente de PRES [PDF]
Revista de la Facultad de Ciencias Médicas de CórdobaIntroducción: la porfiria, es una afección poco común en la que se encuentra alterado el metabolismo del grupo hemo. Caso clínico: joven de 29 años que acude a urgencias por dolor abdominal, vómitos y convulsiones.
Juan Ramon y Cajal Calvo +3 more
doaj +2 more sources
Porfirias agudas: aspectos laboratoriais [PDF]
Revista Brasileira De Ciencia Do Solo, 2002 As porfirias sao causadas por deficiencia parcial de uma das enzimas da via de biossintese do heme, caracterizando-se por disfuncoes neuroviscerais bastante semelhantes. As porfirias agudas sao decorrentes da deficiencia das enzimas delta-aminolevulinato desidratase (ALAD), porfobilinogenio desaminase, coproporfirinogenio oxidase ou protoporfirinogenio
Tatiana Emanuelli
exaly +3 more sources
Furosemide-induced pseudoporphyria in a patient with chronic kidney disease: case report [PDF]
Brazilian Journal of Nephrology, 2018 Introduction: Pseudoporphyria is a rare photodermatosis with characteristics similar to those of porphyria cutanea tarda, without, however, presenting abnormalities in porphyrin metabolism.
Giovana Memari Pavanelli +5 more
doaj +2 more sources
Fluorescent redox-dependent labeling of lipid droplets in cultured cells by reduced phenazine methosulfate [PDF]
Heliyon, 2020 Natural and synthetic phenazines are widely used in biomedical sciences. In dehydrogenase histochemistry, phenazine methosulfate (PMS) is applied as a redox reagent for coupling reduced coenzymes to the reduction of tetrazolium salts into colored ...
Juan C. Stockert +9 more
doaj +2 more sources