Results 51 to 60 of about 65,332 (236)
The Binding of Antibiotics in OmpF Porin [PDF]
Structure, 2013 The structure of OmpF porin in complex with three common antibiotics (zwitterionic ampicillin, anionic ertapenem, and di-anionic carbenicillin) was determined using X-ray crystallography. The three antibiotics are found to bind within the extracellular and periplasmic pore vestibules, away from the narrow OmpF constriction zone.
Ziervogel, Brigitte K., Roux, Benoît
openaire +2 more sources
Frontiers in ImmunologyTuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global health threat, exacerbated by drug resistance and inadequate vaccine efficacy.
Zhijing Zhang +5 more
doaj +1 more source
Biophysical Effects Of Ion Concenteration On The Affinity Between Nanopore, OmpF Lumen and Passing Nucleotide [PDF]
, 2010 OmpF an outer-membrane porin channel of _E. Coli_ posses beta-barrel structure, whose conductivity and gating phenomena are affected by changes in pH, salt concentration and so on. The distribution of amino acids in OmpF induces a non homologous electric
Hamid Mobasheri, Saeid Hadi
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The Complexities of Porin Genetic Regulation
Microbial Physiology, 2010 Our understanding of porin regulation has revealed not only increasing complexity in the regulatory mechanisms, but also that the porin repertoire is more extensive than previously conceived. Initially, the OmpR response regulator was described as the master regulator of porin genes, but many more regulators are involved such as CpxR, PhoB, Lrp, Rob ...
Miguel Angel, De la Cruz, Edmundo, Calva
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Porin fromThiobacillus versutus [PDF]
FEMS Microbiology Letters, 1989 The porin of Thiobacillus versutus IFO 14567 was isolated by extraction of cell-envelopes with sodium dodecyl sulfate. It exhibited strong porin-activity after reconstitution into artificial lipid bilayer membranes. The diameter of the pore was determined as 1.6 nm, with a weak selectivity for cations being observed. The porin migrated as a single band
D, Woitzik +3 more
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A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria [PDF]
, 1994 The novel genetic method of "sheltered RIP" (repeat induced point mutation) was used to generate a Neurospora crassa mutant in which MOM19, a component of the protein import machinery of the mitochondrial outer membrane, can be depleted.
Harkness, Troy A. A. +4 more
core +13 more sources
Conservation of the OmpC Porin Among Typhoidal and Non-Typhoidal Salmonella Serovars
Frontiers in Immunology, 2020 Salmonella enterica infections remain a challenging health issue, causing significant morbidity and mortality worldwide. Current vaccines against typhoid fever display moderate efficacy whilst no licensed vaccines are available for paratyphoid fever or ...
Nuriban Valero-Pacheco +20 more
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mSphere, 2023 Regulation of porin expression in bacteria is complex and often involves small-RNA regulators. Several small-RNA regulators have been described for Burkholderia cenocepacia, and this study aimed to characterize the biological role of the conserved small ...
Andrea M. Sass, Tom Coenye
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The Oligogalacturonate-specific Porin KdgM of Erwinia chrysanthemi Belongs to a New Porin Family [PDF]
Journal of Biological Chemistry, 2002 The phytopathogenic Gram-negative bacteria Erwinia chrysanthemi secretes pectinases, which are able to degrade the pectic polymers of plant cell walls, and uses the degradation products as a carbon source for growth. We characterized a major outer membrane protein, KdgM, whose synthesis is strongly induced in the presence of pectic derivatives.
Blot, Nicolas +4 more
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Borrelia burgdorferi tolerates alteration to P66 porin function in a murine infectivity model
Frontiers in Cellular and Infection MicrobiologyBorrelia burgdorferi exists in a complex enzootic life cycle requiring differential gene regulation. P66, a porin and adhesin, is upregulated and essential during mammalian infection, but is not produced or required within the tick vector.
Christa H. Fierros +13 more
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